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Dededo (Chamorro: Dedidu; formerly in Spanish: [deðeðo]) is the most populated village in the United States territory of Guam. According to the U.S. Census Bureau, Dededo's population was just under 45,000 in 2020. The village is located on the coral plateau of Northern Guam. The greater Dededo-Machanao-Apotgan Urban Cluster had a population of 139,825 as of the 2010 census, making up 87.7% of Guam's population and 29.8% of its area.

Wettengel Rugby Field is a multi-use stadium in Dededo, Guam. It is currently used mostly for rugby and football matches. The stadium holds 1,500 people. It is named for the former Naval Governor of Guam, Ivan Wettengel. It has also held Guam junior rugby middle school games.

The Guam Regional Medical City (GRMC) is a 136-bed private hospital in Dededo, Guam. It is managed under the Philippines-based hospital network, The Medical City. It serves the US territory of Guam as well as neighboring Micronesia, the Northern Marianas, Palau and the Marshall Islands.

Micronesia Mall (Japanese: ミクロネシアモール; Korean: 미크로네시아 몰; Spanish: Centro comercial Micronesia; Russian: Микронезия Молл) is a shopping mall in Dededo, Guam. Located at the intersection of Guam highways 1 and 16, it is the largest shopping center in the United States territory of Guam with over 100 stores and restaurants. The four anchor stores are Ross Dress for Less, two 149,377 sq ft (13,877.6 m2) Macy's stores, which are the only Macy's west of Hawaii, and a 24-hour Payless Supermarket. The mall is also home to stores such as Gap, Guess, Levi's, and Foot Locker. The mall is also home to a 24-restaurant food court and a 12-screen movie theater featuring all stadium 3D/digital technology. Funtastic Park, an amusement park is inside the mall featuring seven rides including a roller coaster, carousel, bumper cars, pirate ship, Crazy Cans, Jungle Safari, Lady Bug and an arcade. Other retail chains include ABC Store, Vitamin World, GNC, Bench, GTA, and Docomo Pacific. Toys "R" Us’ only location in Guam was in this mall up until the 2018 Bankruptcy, the store closed on June 27, with no prior announcement or liquidation sale. Fast food, restaurant and snack chains include Burger King, Panda Express, Cold Stone Creamery, Häagen-Dazs, Denny's, Great American Cookies, KFC, Pretzelmaker, Raising Cane's, Sbarro, Subway, Taco Bell, Tutti Frutti, Chatime, Coffee Beanery, Honolulu Cookie Company, Cinnabon, Pepper Lunch, Robeks, as well as Jollibee and Winchell's Donuts on the outskirts of the mall.

Tumon (Chamorro: Tomhom) is a district located on Tumon Bay along the northwest coast of the United States unincorporated territory of Guam. Located in the municipality of Tamuning, it is the center of Guam's tourist industry.

St. John's School is an international college preparatory school located in the Tumon area of Tamuning, Guam, United States. The school, affiliated with the Episcopal Church in Micronesia, serves students from pre-kindergarten through 12th grade. The school is accredited by the Western Association of Schools and Colleges (WASC) and authorized by the International Baccalaureate Organisation (IBO) to provide the IBO Diploma.

Okkodo High School (Chamorro: Okkodo Mina'takhelo na Eskuela) is a public high school located in Dededo in the United States territory of Guam. The school occupies 62 acres (25 ha) of the island's most populated village, Dededo. Okkodo High School opened its doors on August 21, 2008, making it the fifth public high school under the Guam Department of Education. The school's district encompasses the areas of Astumbo Gardens, Liguan Terrace, NCS/Munoz/Finegayan, Fern Terrace, Machanao, Santa Ana, Harmon Loop, and the surrounding Okkodo area. Okkodo High School is accredited by the Western Association of Schools and Colleges.

Air Manila Flight 702 was an unscheduled passenger flight from Naval Air Station Agana in Guam to Ninoy Aquino International Airport in Manila, carrying 33 passengers and 12 crew members; most of whom were personnel from the base. The Lockheed L-188A Electra attempted takeoff from runway 6L but crashed near a residential area; the crash was caused by retracting the flaps at an altitude too low to clear the terrain after the propeller of engine number three feathered. All 45 people on board and one person on the ground perished in the crash. The investigation concluded that the pilot should have followed company policy by aborting takeoff in the event of an engine failure before reaching VR (takeoff) speed.

UnderWater World Guam is one of the longest tunnel-aquariums in the world and the only oceanarium in the United States territory of Guam. The aquarium opened in 1999 and has more than 2,000 animals representing more than 80 different species. Many of the animals included in the aquarium are native to Guam and the surrounding Marianas Islands. The aquarium is managed and partly owned by U.S. Aquarium Team (USAT) and is located in 1245 Pale San Vitores Road, Tumon, Guam 96911, Mariana Islands]. The main exhibit is a 319-foot-long (97 m) tunnel under an 400,000-US-gallon (1,500,000 L) salt-water aquarium. The aquarium is involved with many conservation efforts on Guam. UnderWater World Guam is a sponsor of the International Coastal Cleanup on Guam every year. The company also started a (now defunct) group known as the Blue Crew, which consists of employees and other individuals from the community focused on environmental education and restoration efforts.

The San Vitores Martyrdom Site, located 0.7 miles south of Bijia Point off Guam Highway 4 in Tamuning, Guam, has significance from 1672. It was listed on the National Register of Historic Places in 1975. It is an important site in marking where Father Diego Luis de San Vitores was killed, and for association with the Spanish-Chamorro Wars against the imposition of Catholic Christianity in Guam. At the time of NRHP listing, the site was marked by a wooden cross and by a historical plaque placed there in 1940.

The Tumon Bay Japanese fortifications are a collection of World War II-era military structures along the coast of Guam in and near the village of Tumon. Many of these structures were listed on the National Register of Historic Places in 1991, using the alternate spelling "Tomhum". They include pillboxes on or close to the beach, and concrete structures and caves located a short way inland on the limestone cliffs that overlook the beach.

The San Vitores Beach Japanese Fortification are the remains of World War II-era defensive positions facing the beach of Tumon Bay on the west side of the island of Guam. Located near the stairs to the beach of the Guam Reef Hotel are the remains of two concrete pillboxes built by Japanese defenders during the occupation period 1941–44. One structure, of which little more than a gun embrasure is discernible, is located in the limestone cliff about 10 metres (33 ft) inland from the high tide line, and a second is located about 10 meters south and 8 meters further inland, with only a section of roof slab and supporting columns recognizable. The defenses were listed on the National Register of Historic Places in 1991. The beach is named after Diego Luis de San Vitores, who was martyred in Tumon Bay.