The EndUp

Blow Buddies was the largest gay sex club in San Francisco, California. Its building was constructed in 1953. It is zoned Service/Arts/Light Industrial (SALI) with a 30 ft height limit, so neither housing nor a hotel can be built here, but affordable housing may be constructed.

The San Francisco Hall of Justice, is the third building to serve as the headquarters of the San Francisco Police Department and San Francisco County Superior Court. It was constructed between 1958 and 1960, in the block bounded by Sixth, Seventh, and Bryant.

Hosfelt Gallery in San Francisco, California was founded in 1996 by Todd Hosfelt to exhibit contemporary international artists working in all media.

San Francisco City Clinic also known as SF City Clinic or usually as City Clinic is a municipal public sexual health clinic specializing in sexually transmitted infections testing and treatment, in addition to advocacy work and medical research. The center is located in the South of Market or "SoMa" district on the north-east side of San Francisco, California, along San Francisco Bay.

Howard Street is a street in San Francisco's South of Market District (SoMa). It begins after branching off from Van Ness Avenue near the Mission District, and then runs parallel to and between of Mission Street (to the North) and Folsom Street (to the South) towards The Embarcadero. Howard Street has the Moscone Center, Rincon Plaza, Yerba Buena Center for the Arts, and The University of San Francisco along its corridor.

The Hugo Hotel was a building in San Francisco's South of Market district built in 1909, designed by Theo W. Lenzen. It was located at 200-214 Sixth Street. Gutted by fire in 1988, Hugo Hotel was notable for being held vacant by the owner for 26 years, and for being the site of the Defenestration of Furniture art installation created in 1997 by local artist Brian Goggin.The San Francisco Redevelopment Agency took the owners to court in 2008. In 2009, the building was acquired by the City and County of San Francisco under a rare claim of eminent domain for $4.6 million.It was finally razed in 2015 to make way for affordable housing; in 2017 the Bill Sorro Community, an apartment house for low-income residents was completed at the site.

Watsi, legally Watsi, Inc., is a nonprofit healthcare crowdsourcing platform that enables individual donors to directly fund medical care for individuals in developing countries without access to affordable medical care.

The InterContinental San Francisco is a high-rise hotel at 888 Howard Street in the South of Market district of San Francisco, California. The 103.63 m (340 ft) 32-story hotel has 550 hotel rooms, and is operated by the InterContinental Hotels Group. The hotel is next to the Moscone West Center, completed in 2003. The hotel opened on February 28, 2008. There is a two-level underground garage and a six-floor podium housing hotel amenities.

Aphotic is a seafood restaurant on Folsom Street in the SoMa neighborhood of San Francisco, California. It has one Michelin star. The restaurant opened in March 2023 and has announced its forthcoming closure in December 2024.

Yerba Buena/Moscone station is an underground light rail station of the San Francisco Municipal Railway's Muni Metro system that is under construction. It is located on the corner of 4th and Folsom streets at the northern end of the South of Market, San Francisco (SoMa) district. Its construction is part of the Central Subway Project and it will be a future station on the T Third Street line. Construction on the station was originally scheduled to be completed in 2017, but was substantially delayed with the rest of the subway. It is scheduled to open in October 2022.

Proof School is a secondary school in San Francisco that offers a liberal arts education intended for students who love mathematics. The school opened in the fall of 2015 with 45 students in grades 6–10. Currently, 121 students in grades 6–12 are enrolled in Proof School for the academic year (2021-2022).

The Tool Box was a leather bar for gay men in San Francisco that operated from 1962 to 1971 on the east corner of 4th Street and Harrison Street. It was the first leather bar in the South of Market, and a meeting spot where influential personalities of the early San Francisco leather scene gathered. After a prominent feature in Life magazine in 1964, it was considered the archetypal leather bar, helping to cement San Francisco's reputation as the “gay capital” of the US. The bar's history was short-lived: from 1965 onwards, the epicenter of the leather scene shifted towards Folsom Street (most notably Febe's bar), which ultimately led to its closing in 1971. The Tool Box is commemorated at the San Francisco South of Market Leather History Alley. The patronage of the Tool Box included influential personalities of the early San Francisco leather scene, among others artist Bill Tellman, Jack H. (owner of the Detour and the Slot, co-owner of Febe's), artist Mike Caffee (creator of the logo and a statue for Febe's), as well as the Satyrs Motorcycle Club (oldest gay motorcycle club in the US) from Los Angeles. The artist Chuck Arnett also worked as a bartender at the Tool Box. On June 26th 1964, Life magazine published a cover story titled "Homosexuality in America", which not only brought San Francisco as a hub of gay life into public consciousness, but also the Tool Box. The article opened with a two-page photo-spread of its interior with patrons dressed in leather beneath a mural, photographed by Bill Eppridge. In the 1991 anthology, Leatherfolk, Jack Fritscher described the article as "an image-liberating historical issue that was read across the nation as an invitation to come to San Francisco and be a man's man." The article also included an interview with Bill Ruquy, part owner of the bar, who detailed the strict dress code that excluded tennis shoes among other garments that didn't fit the biker aesthetic. Especially for queer men living in conservative small towns, the publication shed a spotlight on this gay subculture of butch leathermen, who did not fit the widespread clichés of the 'effeminate homosexual'—and where to find them. Thus, the Life piece unintentionally became an advertisement for the leather scene and ultimately a catalyst of gay emancipation. Drummer magazine dedicated an article about the demolition of the Tool Box in its second volume in August 1975, titled "Requiem for a toolbox". This further illustrates the importance that contemporaries awarded to the Tool Box's role in gay leather history.