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The Botanischer Garten der Universität Karlsruhe is a botanical garden maintained by the Karlsruhe Institute of Technology directorate of Peter Nick. It is located at Am Fasanengarten 2, Karlsruhe, Baden-Württemberg, Germany, and is open weekdays and Sundays; admission is free. The garden contains a total of 5,700 plant species, including 1,930 endangered species per the IUCN Red List or CITES conventions. It has three major missions: Research, particularly in understanding the molecular basis of development, growth, and metabolism, with specific projects in Arabidopsis thaliana, Gnetum gnemon, Nicotiana tabacum, Oryza sativa, and Vitis vinifera. The garden currently cultivates over 50 species of wild grape vines for use in research against downy mildew, as well as a collection of wild rice species from all over the world. Teaching, for which the garden provides plant material for the courses and is used for field trips and the comparison of plant types. Conservation of rare species and varieties of plants, including Althaea hirsuta, Androsace septentivionalis, Apium graveolens, Campanula cervicaria, Cnidium dubium, Equisetum × trachyodon, Gentiana cruziata, Leonurus cardica, Ludwigia palustris, Marsilea quadrifolia, Polystichum braunii, Populus nigra, Salix repens, Scirpus carinatus, Scirpus triqueter, Stipa ioannis, Taraxacum acoriferum, Taraxacum balticiforme, Taraxacum germanicum, Taraxacum pollichii, Trapa natans, Vaccinium x intermedia, Viola uliginosa, and Vitis vinifera L. ssp. sylvestris. It also maintains good collections of succulents and orchids.

Karlsruhe's University of Music (Hochschule für Musik Karlsruhe in German) is a college of music in Karlsruhe, Germany. Originally the Baden Conservatory of Music, it was elevated to a Hochschule under the direction of Franz Philipp, who led the school from 1924 to 1942.

The Hauptfriedhof in Karlsruhe is one of the oldest German communal rural cemeteries. In 1871, the first plans to build a new burial ground outside the city center began. The cemetery was laid out in 1874 by Josef Durm in the Rintheim district, east of the actual city, after the inner-city Alter Friedhof Karlsruhe in the Oststadt had become too small. The main cemetery has grown from its original size of 15.3 hectares in 1873 to over 34 hectares. The graves of more than 32,000 deceased are currently in the cemetery.

Wildparkstadion, currently known as BBBank Wildpark for sponsorship reasons, is a football stadium located in Karlsruhe, Germany. It is the home of the football club Karlsruher SC. It is located northeast of the Karlsruhe Palace (Schloss) and is part of the former deer park (Wildpark) of the Grand Dukes of Baden in the Hardtwald, hence the name. There have been football pitches at the location since 1922, and the stadium was built in 1955, with several major renovations since. A decision to rebuild the stadium was taken in 2006. The City of Karlsruhe and Karlsruher SC became engulfed in disputes about finances and finally abandoned the project in 2014. Two years later, the city again decided to renew the stadium, using the existing site and financed mostly by the city. In November 2018, demolition of parts of the old stadium and the concurrent construction of a new 34,000-seat arena began. Works are being carried out in stages so that matches can be played on the existing pitch in front of at least 15,000 spectators. The new Wildparkstadion is expected to be completed in the first half of 2022 at a projected cost of €123 Million. In 2021, it was announced that BBBank had acquired the naming rights to the stadium for five years.

The Karlsruhe Institute of Technology (KIT; German: Karlsruher Institut für Technologie) is a public research university in Karlsruhe, Germany. The institute is a national research center of the Helmholtz Association.KIT was created in 2009 when the University of Karlsruhe (Universität Karlsruhe), founded in 1825 as a public research university and also known as the "Fridericiana", merged with the Karlsruhe Research Center (Forschungszentrum Karlsruhe), which had originally been established in 1956 as a national nuclear research center (Kernforschungszentrum Karlsruhe, or KfK).KIT is a member of the TU9, an incorporated society of the largest and most notable German institutes of technology. As part of the German Universities Excellence Initiative KIT was one of three universities which were awarded excellence status in 2006. In the following "German Excellence Strategy" KIT was awarded as one of eleven "Excellence Universities" in 2019. KIT is among the leading technical universities in Germany and Europe. According to different bibliometric rankings, KIT is the German university with the strongest research in engineering and natural sciences.In the university part of today's KIT, science-based mechanical engineering was founded in the mid-19th century under the direction of Ferdinand Redtenbacher, which influenced the foundation of other technical universities, such as ETH Zurich in 1855. The university is also among the pioneers of computer science research in Germany. It established the first German faculty for computer science in 1972. On 2 August 1984, the University received the first-ever German e-mail. In the 1990s, all .de domains were registered and managed at the University of Karlsruhe. The same was true for Chinese .cn domains.KIT alumni and faculty include six Nobel Prize laureates and nine Leibniz Prize winners. The Karlsruhe Institute of Technology is well known for many inventors and entrepreneurs who studied or taught there, including Heinrich Hertz, Karl Friedrich Benz and the founders of SAP SE.

Oststadt is the eastern district of Karlsruhe. It is located east of the Durlacher Tor, which borders the city center, and borders the Durlach district to the east.

The 1798 Karlsruhe Synagogue was an early building by the influential architect Friedrich Weinbrenner in the city of Karlsruhe. According to David Brownlee, this "synagogue was the first large Egyptian building to be erected since antiquity." According to Diana Muir Appelbaum, it was "the first public building (that is, not a folly, stage set, or funeral monument) in the Egyptian revival style." Appelbaum writes that the pair of tall pylons are copied from the temple at Karnak. The structure stood until 1871.

Gameforge is a video game publisher and video game developer. It represents a group of companies that operates internationally and has its headquarters in Karlsruhe, Germany. It distributes roughly 20 games, translated into over 50 languages. Their portfolio contains client-based massively multiplayer online games (MMOGs) such as TERA, Metin2, Runes of Magic, and SOLO, as well as browser-based online games such as OGame, Gladiatus, BiteFight, and Ikariam. They also operate mobile games. Gameforge employs a staff of over 300 and was founded by its Chief Executive Officer Alexander Rösner and former CEO Klaas Kersting in 2003.

The Baden State Museum (German: Badisches Landesmuseum) in Karlsruhe is the large cultural, art and regional history museum of the Baden region of Baden-Württemberg . With its globally significant collections, representing more than 50,000 years of international cultural history, it conveys history and historical living environments. Its collections range from prehistory and early history to the Middle Ages and the 21st century. The museum was founded in 1919 and opened in 1921 in the rooms of Karlsruhe Palace.

Karlsruhe Palace (German: Karlsruher Schloss) was built in 1715 for Margrave Charles III William of Baden-Durlach after a dispute with the citizens of his previous capital, Durlach. The city of Karlsruhe has since grown around it. The building is now home to the main museum of the Badisches Landesmuseum.

The Badisches Staatstheater Karlsruhe is a theatre and opera house in Karlsruhe, Germany. It has existed in its present form and place at Ettlinger Tor since 1975. Achim Thorwald became the Intendant in summer 2002 and held that post until the end of the 2010/11 season. Peter Spuhler succeeded him at the beginning of the 2011/12 season and continues to serve in that post. The Staatstheater is a Dreisparten venue, housing three performance genres: musical theatre, ballet and theatre, as well as the studio stage in Karlstraße. The Badische Staatskapelle (orchestra) and the Badische Staatsopernchor (opera chorus) are resident companies of the theatre.

Karlsruhe ( KARLZ-roo-ə, US also KARLSS-, German: [ˈkaʁlsˌʁuːə] (listen); South Franconian: Kallsruh) is the third-largest city of the German state (Land) of Baden-Württemberg after its capital of Stuttgart, and Mannheim, and the 21st-largest city in the nation, with 308,436 inhabitants. It is also a former capital of Baden, a historic region named after Hohenbaden Castle in the city of Baden-Baden. Located on the right bank of the Rhine near the French border, between the Mannheim/Ludwigshafen conurbation to the north and Strasbourg/Kehl to the south, Karlsruhe is Germany's legal center, being home to the Federal Constitutional Court (Bundesverfassungsgericht), the Federal Court of Justice (Bundesgerichtshof) and the Public Prosecutor General of the Federal Court of Justice (Generalbundesanwalt beim Bundesgerichtshof). Karlsruhe was the capital of the Margraviate of Baden-Durlach (Durlach: 1565–1718; Karlsruhe: 1718–1771), the Margraviate of Baden (1771–1803), the Electorate of Baden (1803–1806), the Grand Duchy of Baden (1806–1918), and the Republic of Baden (1918–1945). Its most remarkable building is Karlsruhe Palace, which was built in 1715. There are nine institutions of higher education in the city, most notably the Karlsruhe Institute of Technology (Karlsruher Institut für Technologie). Karlsruhe/Baden-Baden Airport (Flughafen Karlsruhe/Baden-Baden) is the second-busiest airport of Baden-Württemberg after Stuttgart Airport, and the 17th-busiest airport of Germany.