J. Marvin Jones Federal Building and Mary Lou Robinson United States Courthouse

The Potter County Courthouse is a government building for Potter County, located in the county seat of Amarillo, Texas. It was listed on the National Register of Historic Places on August 22, 1996.

The Herring Hotel is one of the oldest buildings in downtown Amarillo, Texas. It was completed in 1926 and was named after the builder and operator, Cornelius Taylor Herring (1849–1931). The building was added to the National Register of Historic Places on January 25, 2024.

The Amarillo Civic Center is a multi-purpose convention center in Amarillo, Texas. It consists of multiple facilities including: A 2,848-seat auditorium with 2,324 permanent seats used for concerts, Broadway shows and other events. The Cal Farley Coliseum, a 4,987-seat multi-purpose arena serving as home to the Amarillo Wranglers of the North American Hockey League and the Amarillo Venom of Champions Indoor Football. The arena, which has 4,879 permanent seats, is also used for concerts, banquets, conventions, ice shows, wrestling and trade shows (the arena features 17,100 square feet (1,590 m2) of floor space). The arena measures 38' 10 from floor to rafters, 50'10 from floor to ceiling. A 16,000-square-foot (1,500 m2) grand plaza, designed as a tribute to Texas and seating up to 1,100 for smaller concerts, banquets, and other special events. It contains a Texas-accented floor, skylight ceiling, and fountains and planters. Two exhibit halls, the North which has 24,565 square feet (2,282 m2) of exhibit space, used for trade shows, conventions, meetings and banquets (capacity is up to 2,200) and with a 25-foot (8 m) ceiling height; and a 26,000-square-foot (2,400 m2), 14-foot (4 m) South Exhibit Hall, also used for similar events. Three meeting rooms—the Heritage, Hospitality, and Regency rooms.There is a memorial statue of the Space Shuttle commander Rick Husband, one of the city's most famous sons, in front of the building.

The Oliver–Eakle–Barfield Building is an historic building located at 600 South Polk Street in Amarillo, Texas. The building was listed on the National Register of Historic Places on January 11, 2019.The building was converted into the Barfield Hotel in 2019.

Hodgetown is a baseball park in downtown Amarillo, Texas. It is the home ballpark of the Amarillo Sod Poodles, the Double-A affiliate of the Arizona Diamondbacks in the Texas League. It opened on April 8, 2019, and can seat 6,631 people. The park is named in honor of Amarillo pharmacist, businessman, philanthropist, and 26th Mayor of Amarillo Jerry Hodge. Hodgetown is the most elevated Double-A ballpark at approximately 3,600 feet above sea level.In the ballpark's inaugural game on April 8, 2019, the Sod Poodles were defeated by the Midland RockHounds, 9–4 in 10 innings. The opener was attended by 7,175 people.

Sacred Heart Cathedral is a former cathedral church located in Amarillo, Texas, United States. It was the seat of the Diocese of Amarillo from 1927 to 1975.

Santa Fe No. 5000 is a 2-10-4 "Texas" type steam locomotive constructed by Baldwin Locomotive Works in 1930 for the Atchison, Topeka and Santa Fe Railway. No. 5000 was immediately nicknamed the "Madame Queen" and remained a unique member of its own class. It was donated to the City of Amarillo, Texas in 1957 and is currently maintained by the Railroad Artifact Preservation Society. Santa Fe 5000 is on the National Register of Historic Places.

FirstBank Southwest Tower is a 374-foot, 31-story building located in Amarillo, Texas, United States. Formerly known as SPS Tower, Bank One Center, Chase Tower, and Amarillo Tower, it is the tallest building in Amarillo and the West Texas region. The building used to be the home of the Amarillo branch of American National Bank. The building also housed the offices of the region's electric power service provider, Southwestern Public Service (which was later acquired by Xcel Energy).The Tower has a striking resemblance to the One Financial Plaza Building in Fort Lauderdale, Florida. The First Bank Southwest Tower is only about three stories taller than its counterpart. In October 2008, the West Texas A&M University letters were installed on the First Bank Southwest Tower as part of the agreement to have university classes there.In 2018, Chase decided to close its downtown Amarillo branch in the building. By June 2018, FirstBank Southwest reached an agreement to locate a downtown branch there and receive naming rights on the building in the process. The FDIC approved the application by October 2018, for FirstBank Southwest to have a branch in the building, and the bank plans to be operational there by the middle of 2019. Work began in late March 2019 to place the letters for the logo sign for FirstBank Southwest at the top of the tower in three places. The process was scheduled to take around two weeks' time.The tower was added to the National Register of Historic Places on March 6, 2019.

The Santa Fe Building is one of the oldest buildings in downtown Amarillo, Texas, U.S.A. It was completed on January 18, 1930 and had the regional offices of the Atchison, Topeka and Santa Fe Railway company. The Amarillo office of the railroad company supervised more than 5,800 miles (9,334 km) of railroads. Brennan Construction Company of Amarillo and Dallas built the building from 1928 to 1930 with an original construction cost of US$1.5 million.The building was vacant more than a decade in the 1990s, until Potter County bought it for $426,000 to gain new office spaces in 1995. It was reopened in 2000, after Potter County spent approximately $14.1 million on renovating the building.

Central Presbyterian Church (also known as First Presbyterian Church) is a historic church at 1100 Harrison Street in Amarillo, Texas. It was built in a Late Gothic Revival, Tudor Revival style and was added to the National Register in 1991.

The Roman Catholic Diocese of Amarillo (Latin: Dioecesis Amarillensis) is a Roman Catholic diocese in Amarillo, Texas. It was founded on August 3, 1926 out of territory taken from the Diocese of Dallas and the Diocese of San Antonio on the same day that the Roman Catholic Archdiocese of San Antonio, its metropolitan see, was elevated to metropolitan status, replacing New Orleans. The Diocese consists of the following 26 counties in the Texas panhandle: Armstrong, Briscoe, Carson, Castro, Childress, Collingsworth, Dallam, Deaf Smith, Donley, Gray, Hall, Hansford, Hartley, Hemphill, Hutchinson, Lipscomb, Moore, Ochiltree, Oldham, Parmer, Potter, Randall, Roberts, Sherman, Swisher, and Wheeler.

JetBlue Flight 191 was a scheduled domestic commercial passenger flight from New York to Las Vegas, United States. On March 27, 2012, the Airbus A320 serving the route diverted to Rick Husband Amarillo International Airport, in Amarillo, Texas, after the captain, suffering from an apparent mental breakdown, started behaving erratically and making disturbing and incoherent statements, leading to the first officer tricking him into entering the cabin where he was restrained by passengers. There were no fatalities.