Sabancı Cultural Center

Atatürk Museum exhibits War of Independence and the first years of Republic at the mansion, Atatürk stayed during his trips to Adana. Overlooking to the Seyhan River, the museum is located on Seyhan Street and it is open to public every day except Mondays. Atatürk's visit to Adana is officially celebrated in this building every year on 15 March.

Adana Cinema Museum (Turkish: Adana Sinema Müzesi) is a museum in Adana, Turkey dedicated to the cinema of Turkey, in particular in relation with directors, actors and producers native to the city. Established in 2011 in a renewed old Adana house, the museum is situated on the west side of Seyhan River. The ground floor of the museum is reserved for the movie posters. At least one name in each poster (director, actor, scriptwriter etc.) belongs to a citizen of Adana. In the first floor, there is a room exhibiting the photos, movie posters and belongings of the renowned Turkish actor Yılmaz Güney (1937-1984). There are life-size figures of Yılmaz Güney, painter Abidin Dino and author Orhan Kemal (1914-1970). Photos and artifacts on display of other well-known people from Adana associated with cinema are writer Yaşar Kemal (born 1923), actor Şener Şen (born 1941) and his father actor Ali Şen (1918-1989), Muzaffer İzgü (born 1933), Ali Özgentürk (born 1947), Orhan Duru, Aytaç Arman (born 1949), Bilal İnci, Meral Zeren, Menderes Samancılar, Nurhan Tekerek and Mahmut Hekimoğlu. There is also a library in the museum.

Sabancı Merkez Camii (English: Sabancı Central Mosque) in Adana is the second largest mosque in Turkey. The exterior of the mosque (and its interior decoration) is similar to the Selimiye Mosque in Edirne, though it has six minarets, similar to the Sultan Ahmed Mosque (Blue Mosque) in Istanbul. The mosque, which went into service in 1998, was constructed upon a confiscated Armenian cemetery. It is built on a total of 52,600 square metres (566,000 square feet) of land and has a closed area of 6,600 square metres (71,000 square feet).Sabancı Central Mosque was built jointly by Turkish Religious Foundation and Sabanci Foundation. The proprietorship of the mosque belongs to Adana Religious Affairs Foundation and its usage rights have been transferred to Adana Provincial Office of Mufti.

The Seyhan River (formerly written Seihan, Sihun; ancient name: Ancient Greek: Σάρος, Sáros), alternatively known as Sarus (or in Turkish as Sarus Su), is the longest river of Cilicia and the longest of Turkey that flows into the Mediterranean Sea. The river is 560 km and flows southwest from its headwaters in the Tahtalı-Mountains (in Sivas and Kayseri provinces) in the Anti-Taurus Mountains to the Mediterranean Sea via a broad delta. Its main tributaries are Zamantı and Göksu, which unite in Aladağ, Adana to form the Seyhan River. The Zamantı River originates from the Uzun Plateau in Pınarbaşı, Kayseri and crosses Tomarza, Develi and Yahyalı districts in Kayseri. Its sources were reported being in the Taurus Mountains in Cataonia. It flowed through Cappadocia by the town of Comana, then through Cilicia. It is noted by numerous ancient authors including Livy, Xenophon, Procopius, Strabo, Ptolemy, Appian, Pliny the Elder, and Eustathius of Thessalonica who erroneously calls it Sinarus.50 km from its mouth, Seyhan River flows through the city of Adana, the only settlement situated on the river. Several bridges and footbridges cross the river in Adana including the Stone Bridge, a 2nd-century Roman bridge. Ancient city of Augusta was also situated on the river, corresponding today to the east side of the Çatalan reservoir. The river meets the Mediterranean Sea at Cape Deli.

Tepebağ (English: Orchard Hill) is a neighbourhood (mahalle) in the municipality and district of Seyhan, Adana Province, Turkey. Its population is 903 (2022). It is a historical neighborhood in the old town of Adana. It is situated on a hill overlooking the Seyhan River on the west, steps away from the Taşköprü, and reflects the traditional housing architecture of the city. Tumulus at Tepebağ is the area of the first settlements in Adana.

Adana American College for Girls was a prominent high school in Adana, Turkey that served from 1880 to 1927. Founded by the American missionary, protestant teachings of the school mostly attracted students from the Armenian community of the city. Adana American College was one of the many missionary schools that were founded during the late 19th century in the Ottoman Empire.

The Great Mosque of Adana (Turkish: Adana Ulu Camii), also known as the Ramazanoglu Mosque Turkish: Ramazanoğlu Camii), is a 16th-century mosque in Adana, Turkey. It forms part of a complex (külliye) that includes a madrasah and a mausoleum (türbe). The buildings are on Kızılay street, next to the Ramazanoğlu Hall.

İstiklal is a historical neighbourhood (mahalle) in the municipality and district of Seyhan, Adana Province, Turkey. Its population is 6,137 (2022). The neighbourhood is part of the downtown of Adana, situated south of the D400 state road and east of the Adana Metro line. İstiklal neighborhood developed west of the Adana's first Central train station that opened in 1886. Several factories, hotels and luxury mansions built rapidly around the station from 1880s to 1910s.

Reşatbey (Turkish pronunciation: [ɾeʃatbej]) is a neighbourhood (mahalle) in the municipality and district of Seyhan, Adana Province, Turkey. Its population is 11,751 (2022). The neighbourhood is part of the downtown, situated north of the D400 state road and west of the Seyhan River.

Ramazanoğlu Hall is the old government residence of the Ramadanids located in Adana. Currently used as a cultural center, it is one of the oldest examples of a mansion in Turkey. Located southeast of the Ulu Camii, it was the Harem of the Ramadanid family and besides being a fine expression of modesty of the emirate, it is also an important work resembling the Mamluk mansions of Egypt.

Surp Asdvadzadzin Cathedral (Armenian: Սուրբ Աստվածածին եկեղեցի, lit. 'Cathedral of the Holy Mother of God'; Turkish: Aziz Meryem Ana Kilisesi), was the Armenian Apostolic cathedral of Adana, Cilicia, during the rule of Ottoman Empire. The cathedral was built in 1840 and had served the Armenian Apostolic community until 1922. Aramian high school and the Armenian Apostolic diocese were also built later in the church property. Surp Asdvadzadzin Cathedral was re-built in 1840 at the site of the former Surp Asdvadzadzin Church that was built in the 13th century during the Armenian Kingdom of Cilicia. In 1890, under the leadership of Adana archbishop Mkrtich Vehapetyan, the Armenians of Adana celebrated the 50th anniversary of the church. The church was called the "Upper Church" back then because of its position being situated on the hill, and St. Stepanos Church was called the "Lower Church" for being on the plain. Major expansion work completed at the church in the early 1900s by the archbishop Muşeğ Seropyan with the support of the Vali Bahri Paşa. The church, thus, was converted into a cathedral and hosted the seat of the archbishop. Aramian high school was also built at this time. After the deportation of Adana Armenians in the course of Armenian genocide, the church building was used as a military depot. With the French rule commenced in 1918, the cathedral was restored to its origin; though after 3 years, Christians had to evacuate Cilicia with the withdrawal of French. The government of Turkey had confiscated the building in 1923 and converted it into a state building. In the 1930s, the building was rented out to Baki Tonguç, a local cinema entrepreneur. He had opened the largest indoor Cinema Hall of Adana, Tan Sineması, which served until late 1960s. The cathedral was demolished in the 1970s, to open space for the construction of the regional headquarters of Turkish Central Bank (Turkish: Merkez Bankası). During the first 50 years of the Republic, Armenian cultural heritage had been largely demolished, destroyed or abandoned in an Anti-Armenian sentiment.

Taşköprü (Italian: Ponte in pietra, English: Stone bridge), historically known as Ponte Sarus, is a Roman bridge spanning the Seyhan River in Adana that was probably built in the first half of the second century AD. The bridge was a key link in ancient trade routes from the Mediterranean Sea to Anatolia and Persia. Until its closure in 2007, it was one of the oldest bridges in the world open to motorized vehicles. Since 2007 it has only carried foot traffic, and now hosts social and cultural events. Among the names used for the bridge during its history are the Saros Bridge, the Bridge of Justinian, the al-Walid Bridge and Taşköprü ("Stone Bridge" in Turkish).