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Bucknell University is a private liberal arts college in Lewisburg, Pennsylvania. Founded in 1846 as the University at Lewisburg, it now consists of the College of Arts and Sciences, the Freeman College of Management and the College of Engineering. It offers 65 majors and 70 minors in the sciences and humanities. Located just south of Lewisburg, the 445-acre (1.80 km2) campus rises above the West Branch of the Susquehanna River. Approximately 3,700 undergraduate students and 50 graduate students attend the university. The school is a member of the Patriot League in NCAA Division I athletics and its mascot is the Bucknell Bison.

Christy Mathewson–Memorial Stadium is a 13,100-seat multi-purpose stadium at Bucknell University in Lewisburg, Pennsylvania. Originally built in 1924, the stadium was renovated and renamed in honor of Mathewson in 1989. It is home to the Bucknell Bison football team from the Patriot League and the Lewisburg Area High School Green Dragons football team. It is named for Christy Mathewson, a Bucknell alumnus who went on to become a Hall of Fame pitcher for the New York Giants in the early 20th century. Mathewson was on the Walter Camp All-American football team as a kicker while a student at Bucknell.

Limestone Run (also known as Bull Run) is a 5.8 miles (9.3 km) tributary of the West Branch Susquehanna River in Union County, Pennsylvania, which flows through East Buffalo Township, Buffalo Township and Lewisburg. Ludwig Derr once constructed a mill on the run, so one of its six tributaries is called Miller Run.

Sojka Pavilion is a 4,000-seat multi-purpose arena in Lewisburg, Pennsylvania. It was built in 2003 and is home to the Bucknell University Bison basketball teams, replacing nearby Davis Gym. It is named for Dr. Gary Allan Sojka, a former president of the university who remained at the university as a professor of biology after the end of his term, until his retirement in 2006. It features locker rooms, a hardwood playing surface, concession stands, LED video boards, a team store, and a Jumbotron. In 2006, 2011, 2012, 2013, 2017 and 2018, Sojka Pavilion hosted the Patriot League men's basketball tournament championship final game.

Miller Run is a tributary of Limestone Run in Union County, Pennsylvania, in the United States. It is approximately 1.2 miles (1.9 km) long and flows through East Buffalo Township and Lewisburg. The watershed of the stream has an area of 0.87 square miles (2.3 km2). The stream has no officially named tributaries. It is very small and is not a perennial stream, but is impacted by stormwater flows and also has high concentrations of sediment. The stream's chemical hydrology has been significantly affected by human use. Major rock formations in its watershed include the Bloomsburg Formation, the Keyser-Tonoloway Formation, and the Wills Creek Formation. Most of the watershed of Miller Run is owned by Bucknell University. A significant fraction of the watershed is on urban land, but there is also some forested land. The stream was being channelized as early as the 1930s. In the 21st century, a number of studies and restoration projects have been done on it. The stream is a Warmwater Fishery and six fish species have been observed within it, though only one is found in its lower reaches. It has a very low concentration of benthic macroinvertebrates.

Kinney Natatorium is a multi-purpose natatorium located in Lewisburg, Pennsylvania. The venue hosts home meets for the Bucknell Bison men's and women's swimming and diving teams and water polo teams. Kinney Natatorium was opened in 2002 and also host the PIAA swimming and diving championships annually.

Davis Gym is an indoor athletics facility on the campus of Bucknell University in Lewisburg, Pennsylvania. It is currently home to Bucknell Bison volleyball and wrestling. It was the primary venue for basketball and other indoor sports until the Sojka Pavilion opened in 2003. It hosted the Patriot League men's basketball tournament title game in 1993. Following renovations in the 1990s to add reserved seats, Davis Gym's listed capacity was 2,500, though on occasion standing room crowds exceeded that.Davis Gym is named for John Warren Davis, class of 1896 and chairman of the board of trustees at the time of its opening. It was dedicated in his honor in 1938. The gym replaced Tustin Gymnasium (now Tustin Hall), built in 1890. The building, located on the northern edge of campus with the Lewisburg Cemetery behind it, has a barrel vault ceiling, with end zone scoreboards and seating above the sides of the court. Formerly, bleachers were located courtside during its time as a basketball gym, and a stage was located at the rear (northwest) end of the building but has since been blocked off.

The Lewisburg Armory is an historic National Guard armory that is located in East Buffalo Township, Union County, Pennsylvania. It was added to the National Register of Historic Places in 1991.

The Lewisburg Historic District is a national historic district that is located in Lewisburg, Union County, Pennsylvania. It was added to the National Register of Historic Places in 2004.

Lewisburg is an historic, American railroad freight station that is located in Lewisburg, Union County, Pennsylvania.

Chamberlin Iron Front Building is a historic commercial building located at Lewisburg, Union County, Pennsylvania. It was built in 1868, and is a three-story, brick building with a two-story rear addition in the Italianate style. It measures 56 feet wide and 160 feet deep. The main section has a flat roof and the addition a gable roof. It features a cast-iron front manufactured in Danville, Pennsylvania. Over the years the building has housed a general store, shoe store, feed store, and post office, as well as fraternal organizations on the upper floors.It was listed on the National Register of Historic Places in 1979. It is located in the Lewisburg Historic District.

Eugene B. Depew Field is a baseball venue located on the campus of Bucknell University in Lewisburg, Pennsylvania, USA. It is home to the Bucknell University Bison college baseball team of the Division I Patriot League. The field has a seating capacity of 500 spectators and was built in 1990.