80th Street station (IRT Second Avenue Line)

H&H Bagels is a bagel company in New York City that has been described as "classic," "famous," and "iconic." The original store has closed, but five retail locations on the Upper East Side and Upper West Side of Manhattan and at John F. Kennedy International Airport, LaGuardia Airport, and Moynihan Train Hall are currently open daily. With these stores and its nationwide shipping and wholesale businesses, H&H Bagels is one of the largest bagel manufacturers in New York City.

Etats-Unis was a restaurant in New York City. The restaurant had received a Michelin star, before closing.

The Comic Strip Live is the oldest stand-up comedy showcase club in New York City, located at 1568 Second Avenue (between 81st and 82nd Streets).

King's Carriage House is a New American cuisine restaurant, tea room, and wine bar located at 251 East 82nd Street (between Second Avenue and Third Avenue), on the Upper East Side in Manhattan, in New York City.It opened in 1995. It is owned by Elizabeth King (a chef) and Paul Farrell (who runs the dining room).

Temple Shaaray Tefila (Hebrew: שערי תפילה – Gates of Prayer) is a traditionally oriented Reform synagogue located at 250 East 79th Street (at the corner of 2nd Avenue) on the Upper East Side in Manhattan, New York City.The synagogue was founded in 1845, and was officially chartered in 1848. It moved to its current location in 1959. It has over 1,200 family member units, and over 800 students combined in its religious school and early childhood programs.

Orwasher's Bakery is a famous breadmaking business in New York City that has been listed among the top ten bakeries in America. Also known as A. Orwasher Handmade Bread Inc. it was established in 1916 on 78th Street in the Yorkville area of the New York City borough of Manhattan and it is now one of the last vestiges of the thriving immigrant population that lived in that area around the start of the 20th century.

The Yorkville Branch of the New York Public Library was built in 1902. It was added to the National Register of Historic Places in 1982.

The Church of St. Elizabeth of Hungary is a Roman Catholic parish church in the Roman Catholic Archdiocese of New York, located at 211 East 83rd Street, between Second and Third Avenues, on the Upper East Side of Manhattan, New York City.

Brasserie Julien was a brasserie-style French cuisine restaurant located at 1422 Third Avenue (between East 80th Street and East 81st Street) on the Upper East Side of Manhattan in New York City, as well as a jazz club. The establishment closed at the end of 2012.

Dorrian's Red Hand, also known simply as Dorrian's, is a famed Irish-American bar located at 1616 Second Avenue at East 84th Street, on the Upper East Side of Manhattan, New York City, New York.Started by Irish immigrant James "Red Dog" Dorrian in 1960 and operated by his son Jack, the popular hangout became a social pillar for preppy Upper East Side teenagers, college students, and young urban professionals. It is known for its "old time" atmosphere and the chummy and clubby demeanor of its patrons. Today, the bar is still family-owned and managed by Jack Dorrian's son, Jimmy. Dorrian's has expanded to a second location in Jersey City, New Jersey. Dorrian's Red Hand is a common hang out for the players of the New York Yankees.

The houses at 208–218 East 78th Street in Manhattan, New York, United States, are a group of six attached brick rowhouses built during the early 1860s, on the south side of the street between Second and Third Avenues. They are the remnant of 15 built along that street as affordable housing when the Upper East Side was just beginning to be developed. They are distinctive for the round-arched windows and door openings on their north (front) facades, an unusual trim for houses otherwise firmly in the Italianate architectural style common for urban buildings of that era. They are the second oldest group of buildings on the Upper East Side after the East 78th Street Houses a block to the east, but unlike that row they retain more of their original appearance. In 1978 they were designated New York City landmarks, and in 1983 they were listed on the National Register of Historic Places.

The Church of St. Monica, commonly referred to as St. Monica's, is a parish church in the Roman Catholic Archdiocese of New York, located at 413 East 79th Street, Manhattan, New York City. The parish was established in 1879 and in 2015 merged with nearby St. Elizabeth of Hungary and St. Stephen of Hungary churches.