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The American Nurses Association (ANA) is a 501(c)(6) professional organization to advance and protect the profession of nursing. It started in 1896 as the Nurses Associated Alumnae and was renamed the American Nurses Association in 1911. It is based in Silver Spring, Maryland and Jennifer Mensik Kennedy PhD, RN, NEA-BC, FAAN is the current president. The ANA states nursing is the protection, promotion, and optimization of health and abilities, prevention of illness and injury, alleviation of suffering through the diagnosis and treatment of human response, and advocacy in the care of individuals, families, communities, and populations.

Street Law (also known as StreetLaw) is a global program of legal and civics education geared at secondary school students. Street Law is an approach to teaching practically relevant law to grassroots populations using interactive teaching methodologies. Elements of practical law taught include awareness of human rights/civil rights, criminal breaches and transgression, democratic principles, conflict resolution, the advocacy process, criminal and civil law, employment and labour law, family law, and consumer rights.

The Association of University Centers on Disabilities (AUCD) is an American institution that operates in the disability field, instituted after the Community Mental Health Act of 1963. Currently, AUCD is a network that represents 67 University Centers for Excellence in Developmental Disabilities (UCEDD) in every state and territory in the United States. AUCD has also established 43 Maternal and Child Health (MCH), Leadership Education in Neurodevelopmental and Related Disabilities (LEND) programs, and 15 Eunice Kennedy Shriver Intellectual and Developmental Disabilities Research Centers (IDDRC).

Ellsworth Place is a 350,000-square-foot (33,000 m2), six-story, enclosed vertical power center in downtown Silver Spring, Maryland. It opened as City Place Mall on April 2, 1992, and is located at the intersection of Fenton Street and Colesville Road (U.S. Route 29). Dave and Buster's opened in November 2016.The shopping center is located in downtown Silver Spring, which underwent densification and renovation from around 2005 through 2020, resulting in a retail, dining and entertainment hub for the Washington metropolitan area. Ellsworth Place anchors include a two-story Burlington Coat Factory, Dave & Buster's, (as of August 2022) DSW, Five Below, Marshalls, Michaels, Ross Dress for Less and TJ Maxx. An initial redevelopment in the early 2000s saw the addition of a row of street-level shops, including PNC Bank, MOD Pizza, Chipotle Mexican Grill, and Ben & Jerry's.

The AFI Docs (formerly Silverdocs) documentary film festival is an American international film festival created by the American Film Institute and the Discovery Channel. It is held every year in Silver Spring, Maryland and Washington, D.C. Started in 2003, the festival is held for five days in June at the AFI Silver Theatre as well as several locations in Washington, D.C.

AFI Silver Theatre and Cultural Center or commonly known as AFI Silver is a three-screen movie theater complex in downtown Silver Spring, Maryland, north of Washington, D.C.

The Brigadier General Charles E. McGee Library, formerly the Silver Spring Library, is part of the Montgomery County Public Libraries System. It opened to the public in 1931 and is currently located at 900 Wayne Avenue in Silver Spring, Maryland. The library is named for Charles E. McGee, a Tuskegee Airman who had lived in Montgomery County.

Silver Spring Library is a light rail station that is currently under construction. It will be part of the Purple Line in Maryland.

The National Weather Service (NWS) is an agency of the United States federal government that is tasked with providing weather forecasts, warnings of hazardous weather, and other weather-related products to organizations and the public for the purposes of protection, safety, and general information. It is a part of the National Oceanic and Atmospheric Administration (NOAA) branch of the Department of Commerce, and is headquartered in Silver Spring, Maryland, within the Washington metropolitan area. The agency was known as the United States Weather Bureau from 1890 until it adopted its current name in 1970.The NWS performs its primary task through a collection of national and regional centers, and 122 local Weather Forecast Offices (WFOs). As the NWS is an agency of the U.S. federal government, most of its products are in the public domain and available free of charge.

The Office of Ocean Exploration Research (OER) is a division of the United States National Oceanic and Atmospheric Administration (NOAA). It is run under the auspices of the Office of Oceanic and Atmospheric Research (OAR). The Office facilitates ocean exploration by supporting expeditions, exploration projects, and related field campaigns. The OER mission has four components: Mapping the physical, biological, chemical and archaeological aspects of the ocean; Understanding ocean dynamics at new levels to describe the complex interactions of the living ocean; Developing new sensors and systems to regain U.S. leadership in ocean technology; Reaching out to the public to communicate how and why unlocking the secrets of the ocean is well worth the commitment of time and resources, and to benefit current and future generations.

The Association of Zoos and Aquariums (AZA), originally the American Association of Zoological Parks and Aquariums, is an American 501(c)(3) nonprofit organization founded in 1924 and dedicated to the advancement of zoos and public aquariums in the areas of conservation, education, science, and recreation. AZA is headquartered in Silver Spring, Maryland, United States, and accredits zoos. There were 238 accredited facilities as of 2019, primarily in the US, and also a handful in eleven other countries.

Silver Spring is a Washington Metro and MARC Train station in Montgomery County, Maryland on the Red Line and Brunswick Line. On the Metro, Silver Spring is the first station in Maryland of the eastern end of the Red Line, and is the second-busiest Metro station in Maryland after Shady Grove. North of this station, it goes underground as it heads towards the underground terminus of Glenmont. Silver Spring serves the suburb of Silver Spring, and is located east of the intersection between Colesville Road (Route 384) and East-West Highway (Route 410). In addition to rail service, several Metrobus and Ride On bus routes also serve the station at the Paul S. Sarbanes Transit Center, formerly known as the Silver Spring Transit Center. Silver Spring will be a stop for the Purple Line light rail system, which is currently under construction.