Christopher C. Kraft Jr. Mission Control Center

The Lyndon B. Johnson Space Center (JSC) is NASA's center for human spaceflight in Houston, Texas (originally named the Manned Spacecraft Center), where human spaceflight training, research, and flight control are conducted. It was renamed in honor of the late US president and Texas native, Lyndon B. Johnson, by an act of the United States Senate on February 19, 1973. It consists of a complex of 100 buildings constructed on 1,620 acres (660 ha) in the Clear Lake Area of Houston, which acquired the official nickname "Space City" in 1967. The center is home to NASA's astronaut corps, and is responsible for training astronauts from both the US and its international partners. It houses the Christopher C. Kraft Jr. Mission Control Center, which has provided the flight control function for every NASA human spaceflight since Gemini 4 (including Apollo, Skylab, Apollo–Soyuz, and Space Shuttle). It is popularly known by its radio call signs "Mission Control" and "Houston". The original Manned Spacecraft Center grew out of the Space Task Group (STG) headed by Robert R. Gilruth that was formed to coordinate the US crewed spaceflight program. The STG was based at the Langley Research Center in Hampton, Virginia, but reported organizationally to the Goddard Space Flight Center just outside Washington, D.C. To meet the growing needs of the US human spaceflight program, plans began in 1961 to expand its staff to its own organization, and move it to a new facility. This was constructed in 1962 and 1963 on land donated by the Humble Oil company through Rice University, and officially opened its doors in September 1963. Today, JSC is one of ten major NASA field centers.

The Space Environment Simulation Laboratory (SESL) is a facility in Building 32 at the Lyndon B. Johnson Space Center that can perform large-scale simulations of the vacuum and thermal environments that would be encountered in space. Built in 1965, it was initially used to test Apollo Program spacecraft and equipment in a space environment, and continues to be used by NASA for testing equipment. It was designated a National Historic Landmark in 1985.

The Johnson Space Center shooting was an incident of hostage taking that occurred on April 20, 2007 in Building 44, the Communication and Tracking Development Laboratory, at the Lyndon B. Johnson Space Center (JSC) in Houston, Texas, United States. The gunman, William Phillips, an employee for Jacobs Engineering who worked at Building 44, shot and killed one person and took a hostage for over three hours before committing suicide. Police said Phillips was under review for poor job performance and he feared being dismissed.

The Lunar Sample Laboratory Facility (LSLF) is a repository and laboratory facility at NASA's Lyndon B. Johnson Space Center in Houston, Texas, opened in 1979 to house geologic samples returned from the Moon by the Apollo program missions to the lunar surface between 1969 and 1972. The facility preserves most of the 382 kilograms (842 lb) of lunar material returned over the course of Apollo program and other extraterrestrial samples, along with associated data records. It also contains laboratories for processing and studying the samples without contamination.

Houston Methodist Clear Lake Hospital, located in Nassau Bay, Texas, across from Johnson Space Center, is one of seven community hospitals that are part of Houston Methodist. It employs about 900 people, has an estimated 700 affiliated doctors and admits more than 5,700 patients annually. The hospital serves the Greater Bay area.

Space Shuttle Independence, formerly known as Explorer, is a full-scale, high-fidelity replica of the Space Shuttle. It was built by Guard-Lee in Apopka, Florida, installed at Kennedy Space Center Visitor Complex in 1993, and moved to Space Center Houston in 2012. It was built using schematics, blueprints and archival documents provided by NASA and by shuttle contractors such as Rockwell International. While many of the features on the replica are simulated, some parts, including the landing gear's Michelin tires, have been used in the Space Shuttle program. The model is 122.7 ft (37.4 m) long, 54 ft (16 m) high, has a 78 ft (24 m) wingspan, and weighs 171,860 lb (77,950 kg).

Space Center Houston is a science museum that serves as the official visitor center of NASA Johnson Space Center in Houston. It was designated a Smithsonian Affiliate museum in 2014. The organization is owned by NASA, and operated under a contract by the nonprofit Manned Spaceflight Education Foundation, a 501(c)(3) organization. The Johnson Space Center is the home of Mission Control and astronaut training.The center opened in 1992 replacing the former Visitor Center in Johnson Space Center Building 2. The museum is 250,000 square feet (23,000 m2) and displays over 400 space artifacts, including the Mercury 9, Gemini 5, and Apollo 17 space capsules.

Nassau Bay is a city in Harris County, Texas, United States, bordering the outermost southeastern edge of the city of Houston. It is located in the Clear Lake Area near Galveston Bay, directly adjacent to the Lyndon B. Johnson Space Center. The population was 5,347 at the 2020 census.

The Bay Area Museum is located in Clear Lake Park in Seabrook, Texas, US, part of the Clear Lake area, Bay Area Houston. The museum displays changing exhibits that reflect the history of the area, as well as conserving memorabilia from the Lunar Rendezvous festival, an annual celebration of the region's link to space exploration due to the presence of the Johnson Space Center.

Clear Lake City is a master-planned community located in southeast Harris County, Texas, within the Bay Area of Greater Houston. It is the second-largest master-planned community in Houston – behind Kingwood. The majority of the community lies in the corporate limits of Houston, and a small eastern portion within the city limits of Taylor Lake Village.The community is adjacent to NASA's Johnson Space Center, as well as other major aerospace companies—including Boeing and Lockheed-Martin. The community and its adjacent areas have a high concentration of engineers due to both NASA and the local petrochemical and biomedical industries.

Endeavour is a 30-story high-rise condominium building in Pasadena, Texas, in southeastern Greater Houston. The building was built in 2008 on the shore of Clear Lake, originally envisioned to be the first of a number of high-rise residential buildings that would be built on the waterfront of the generally low-rise suburban area near the Johnson Space Center. However, damage from Hurricane Ike in late 2008, combined with the property-market downturn of the 2008 financial crisis, led to the developer filing for bankruptcy in May 2009, having sold only 36 of the 80 units. The remaining 44 units were purchased in bankruptcy court in December 2009 by an investment partnership, for $9.5 million plus past-due taxes. The new owners repaired and renovated the building at a cost of $2 million, and relaunched condominium sales in 2010.

The University of Houston–Clear Lake (UHCL) is a public university in Pasadena and Houston, Texas, with branch campuses in Pearland and Texas Medical Center. It is part of the University of Houston System. Founded in 1971, UHCL had an enrollment of more than 9,000 students for fall 2019.The university serves students in four academic colleges. UHCL offers 97 degree programs: 46 bachelors, 48 masters, and three doctoral. Awarding more than 2,100 degrees annually, the university's alumni base exceeds 73,000.