Columbarium of Pomponius Hylas

The Tomb of the Scipios (Latin: sepulcrum Scipionum), also called the hypogaeum Scipionum, was the common tomb of the patrician Scipio family during the Roman Republic for interments between the early 3rd century BC and the early 1st century AD. Then it was abandoned and within a few hundred years its location was lost. The tomb was rediscovered twice, the last time in 1780 and stands under a hill by the side of the road behind a wall at numbers 9 and 12 Via di Porta San Sebastiano, Rome, where it can be visited by the public for a small admission fee. The location was privately owned on discovery of the tomb but was bought by the city in 1880 at the suggestion of Rodolfo Amedeo Lanciani. A house was subsequently built in a previous vineyard there. The current main entrance to the tomb is an arched opening in the side of the hill, not the original main entrance. After discovery the few surviving remains were moved and interred with honor elsewhere or unknowingly discarded. The moveables—the one whole sarcophagus and the fragments of other sarcophagi—were placed on display in the hall of the Pio-Clementino Museum at the Vatican in 1912. The sepulchre is a rock-cut chambered tomb on the interior, with the remains of a late façade on the exterior. During the republic the tomb stood in a cemetery for notables and their families located in the angle between the Via Appia and the Via Latina on a connecting road joining the two just past the branch point. It was originally outside the city not far from where the Via Appia passed through the Servian Wall at the Porta Capena. In subsequent centuries new construction changed the landmarks of the vicinity entirely. The wall was expanded to become the Aurelian Wall through which the Porta Appia admitted the Via Appia. The cemetery was now inside the city. The Appian gate today is called the Porta San Sebastiano. Before it is the so-called Arch of Drusus, actually a section of aqueduct. The Via Appia at that location was renamed to the Via di Porta San Sebastiano. It passes through the Parco degli Scipioni where the cemetery once was located. The via is open to traffic. Most of it is lined by walls.

The Aurelian Walls (Italian: Mura aureliane) are a line of city walls built between 271 AD and 275 AD in Rome, Italy, during the reign of the Roman Emperor Aurelian. They superseded the earlier Servian Wall built during the 4th century BC. The walls enclosed all the seven hills of Rome plus the Campus Martius and, on the right bank of the Tiber, the Trastevere district. The river banks within the city limits appear to have been left unfortified, although they were fortified along the Campus Martius. The size of the entire enclosed area is 1,400 hectares (3,500 acres). The wall cut through populated areas: in reality the city at the time embraced 2,400 hectares (5,900 acres). Pliny the Elder in the first century AD suggested that the densely populated areas, extrema tectorum ("the limits of the roofed areas") extended 2.8 kilometres (1.7 mi) from the Golden Milestone in the Forum (Natural History 3.67).

San Cesareo in Palatio or San Caesareo de Appia [san tʃeˈzaːreo de ˈappja] is a titular church in Rome, near the beginning of the Appian Way. It is dedicated to Saint Caesarius of Terracina, a 2nd-century deacon and martyr.

San Giovanni a Porta Latina (Italian: "Saint John Before the Latin Gate") is a Basilica church in Rome, Italy, near the Porta Latina (on the Via Latina) of the Aurelian Wall.

San Giovanni in Oleo is a chapel adjacent to the church of San Giovanni a Porta Latina in Rome. It commemorates the place where, according to legend, in 92 CE, at the hands of the emperor Domitian, the apostle John was immersed in a vat of boiling oil from which he emerged unharmed. Tradition relates that, having failed to execute the apostle, Domitian exiled him to the island of Patmos where John wrote the biblical Book of Revelation. It is supposed that John later died and was buried in Ephesus where a large basilica was built to house his relics. He is held to be the only one of the Twelve Disciples to have been spared from martyrdom. Although the current building is not ancient, the small centralized form - customarily employed by the Romans for martyria, mausolea and other memorial purposes - may have been inspired by an earlier structure. Documentary sources seem to indicate that San Giovanni a Porta Latina was in existence by the end of the 5th century. The present octagonal chapel was built circa 1509. The design was commonly ascribed to the architect Donato Bramante, although it is now thought to have been the work either of Antonio da Sangallo the Younger or Baldassare Peruzzi. In 1658, it was remodeled by Borromini who added the frieze and the elaborate finial (the original of which is now preserved in the portico of the church nearby).. On the door is the coat of arms of the French prelate Benoît Adam, with the motto "Au plaisir de Dieu". The frescos depicting Saint John's attempted execution were painted by Lazzaro Baldi in 1716.

Porta Ardeatina was one of the gates of the Aurelian Walls in Rome (Italy).The gate was built in the time of Nero. It stands at an angle in the Aurelian Walls.It was placed in a halfway point between Porta Appia and Porta San Paolo, close to the modern arches under which Via Cristoforo Colombo runs. The gate was probably locked very soon (it is no more mentioned starting from 8th century); on the base of the present remains, it can arguably be classified as a simple postern, framed with travertine, whose most interesting characteristic is the presence, both inside and outside the wall, of a stretch of paved road dating from the Roman period, in which the tracks left by carts traffic – that should have been quite intense – are still visible. The gate had no defensive towers: this lack was fixed by means of a projection of the wall, which could therefore serve as a little rampart. According to a statement by the humanist and historian Poggio Bracciolini, Porta Ardeatina bore the usual memorial plate, commemorating the restoration carried out by Emperor Honorius in 401–403. This could indicate that it was not just a simple secondary passage, but a real single-arch gate. Close to the gate, on the inner side, remains of a grave incorporated into the wall are visible: this is consistent with the project of Emperor Aurelian who, in order to lessen the costs and speed up the building of the wall circle, integrated former structures within the wall itself.

The Arch of Drusus is an ancient arch in Rome, Italy, close to the First Mile of the Appian Way and next to the Porta San Sebastiano. Long misidentified, it is most likely the remains of the Arch of Trajan.

The Porta Latina (Latin - Latin Gate) is a single-arched gate in the Aurelian Walls of ancient Rome.

The Museo delle Mura ("museum of the walls") is an archaeological museum in Rome, Italy. It is housed in the first and second floors of the Porta San Sebastiano at the beginning of the Appian Way. It provides an exhibition on the walls of Rome and their building techniques, as well as the opportunity to walk along the inside of one of the best-preserved stretches of the Aurelian Wall. The museum is free of charge.

The Porta San Sebastiano is the largest and one of the best-preserved gates passing through the Aurelian Walls in Rome (Italy).

The Basilica of San Sisto Vecchio (in Via Appia) is one of the over sixty minor basilicas among the churches of Rome, and a titular church since 600 AD. As such, it is connected to the title of a Cardinal priest, currently Antoine Kambanda.

Santi Nereo ed Achilleo is a fourth-century basilica church in Rome, Italy, located in via delle Terme di Caracalla in the rione Celio facing the main entrance to the Baths of Caracalla. It has been the titular church of Cardinal Celestino Aós Braco since 28 November 2020. Note that the cemetery church of the catacomb of Saint Domatilla on the Appian Way, virtually lost in the early Middle Ages and rediscovered in the 1870s by the archaeologist Giovanni Battista de Rossi, carries the same dedication to Nereo and Achilleo.