SoHo, Manhattan

The St. Nicholas Hotel was a 600-room, mid-nineteenth century luxury hotel on Broadway in the neighborhood of SoHo in Manhattan, New York City. It opened on January 6, 1853, and by the end of the year had expanded to 1,000 rooms. The St. Nicholas raised the bar for a new standard of lavish appointments for a luxury hotel. It was the first New York City building to cost over US$1 million. The hotel was said to have ended the Astor House's preeminence in New York hostelry.

The Eleanor Ettinger Gallery was a private art gallery in SoHo, Manhattan. The gallery was founded in 1975 by Eleanor Ettinger. The gallery had started as a home for fine art lithography, with Norman Rockwell as the first artist to host an exhibition there. Notable artists that were exhibited at the Eleanor Ettinger Gallery included Malcolm T. Liepke, Alice Neel, and R. Kenton Nelson.The Eleanor Ettinger Gallery was later owned and run by Eleanor Ettinger's daughter, Frann Bradford, and Frann's husband James Umphlett. They had an interest in realism, and representational and contemporary art, and this was reflected in the work exhibited during their time running the gallery. In July 2010, they decided to move the gallery out of SoHo, and opened new two locations in Midtown on 57th Street and in Chelsea on 25th Street. The Eleanor Ettinger Gallery closed in 2013.

The New Era Building is an 1893 Art Nouveau commercial loft building at 495 Broadway, between Spring Street and Broome Street, in the SoHo section of Manhattan in New York City.

Mimi Ferzt was a contemporary art space in SoHo, Manhattan, New York City. It exhibited Eastern European artists such as Mihail Chemiakin, Nikolai Makarov and Oscar Rabine, as well maintained a roster of Soviet dissident artists who were seeking refuge in the United States. It is permanently closed.The gallery helped establish the careers and expand the cultural footprint for members of the Soviet non-conformist art movement.

The Theatre Comique, formerly Wood's Minstrel Hall, was a venue on Broadway in Manhattan, New York City. It was built in 1862, replacing a synagogue on the site.

The E.V. Haughwout Building is a five-story, 79-foot (24 m) tall commercial loft building in the SoHo neighborhood of Manhattan, New York City, at the corner of Broome Street and Broadway. Built in 1857 to a design by John P. Gaynor, with cast-iron facades for two street-fronts provided by Daniel D. Badger's Architectural Iron Works, it originally housed Eder V. Haughwout's fashionable emporium, which sold imported cut glass and silverware as well as its own handpainted china and fine chandeliers, and which attracted many wealthy clients – including Mary Todd Lincoln, who had new official White House china painted here. It was also the location of the world's first successful passenger elevator.

Yellow Rat Bastard is the flagship establishment in a chain of New York City retail clothing stores and print magazine owned by Henry Ishay. It specializes in hip hop and alternative-style clothing and shoes.

The Museum of Women is scheduled to open in a five floor building that was formerly home to Topshop at 480 Broadway in SoHo in the summer of 2022. The museum was founded by Abby Trott and will offer interactive exhibits and a gift shop featuring products made by women. Its physical location is expected to run through the end of 2022 at least and will explore issues faced by women in contemporary society and culture.

Environ was a performance space that was influential during the Loft Jazz scene of the mid-1970s in NYC. It was located on Broadway in SOHO and close to two other noted Loft Jazz venues: RivBea and Ali's Alley. Environ was established by Chris Brubeck and Danny Brubeck sons and band mates of noted jazz musician Dave Brubeck. Environ was managed by John Fischer pianist leader of Interface with assistance by staff Mark Forman indie media producer and Brian Olewnick music blogger and reviewer for Bagatellen. Environ offered performance space to many Loft Jazz musicians, dancers and other performance artists. Dave Holland (former Miles Davis bassist), Anthony Braxton, Charles Tyler, Hamiet Bluiett, David Murray, Lester Bowie, Joseph Bowie, Chico Freeman were some of the many free jazz artists that performed there. James Siegfried, who was later to become better known as James Chance, and the Contortions (part of the No Wave scene in NYC) had his debut there. Environ attracted many of the future avant-garde jazz and No Wave musicians to its stage and audience. Muhal Richard Abrams one of the founders of the AACM practiced there regularly on the house piano.

Greene St. Recording was a New York City recording studio, located at 112 Greene Street in SoHo, Manhattan, until its closure in 2001. It was one of the early headquarters of hip hop music during the 1980s and 1990s.

The Gunther Building is an historic building at 469 Broome Street on the corner of Greene Street in the SoHo neighborhood of Manhattan, New York City.

Balthazar is a French brasserie restaurant located at 80 Spring Street (between Broadway and Crosby Street) in SoHo in Manhattan, in New York City. It opened on April 21, 1997, and is owned by restaurateur Keith McNally.: 182 McNally also owns Pastis, Cafe Luxembourg, Lucky Strike, the Russian-themed bar and restaurant Pravda, Odeon in Tribeca, and Schiller's Liquor Bar on the Lower East Side. Balthazar Bakery was later opened, at 80 Spring Street.McNally opened Balthazar in the theater district in Covent Garden in London, in February 2013. Balthazar London will reside within a building known as The Flower Cellars, sharing the space with The London Film Museum. The general manager will be Byron Lang.