Church and monastery of El Carmen Alto, Quito

The City Museum (Museo de la Ciudad) is a museum in the colonial center of Quito, Ecuador. It is located on Garcia Moreno Street, between Morales and Rocafuerte. The museum was founded in 1998 and occupies the buildings of what once was the San Juan de Dios Hospital. The buildings were designated as a UNESCO Cultural World Heritage Site. and were restored in 1995 using the same materials as the original buildings to repair damaged areas. Ancient stone Doric columns, stone doorways and stone coverings in the patios are a highlight of the architecture.The museum chronicles the history of Quito, along with 400 years of the history of the hospital. The former hospital buildings include an area of 10,200 square meters which house the four museum collections, 10 exhibition halls, workshop areas and museum offices, arranged around four courtyards. In addition to its permanent collections, the museum also offers the temporary exhibitions, focusing on particular aspects of life in Quito.In July 2020, a collection of 69 artifacts were privately restituted to Ecuador to be displayed and appreciated at the museum. The objects were first taken from Ecuador by a London diplomat in the 1960s who was an art and archaeology enthusiast. The objects in his collection include Catholic icons from the era of the Spanish conquest and objects thought to date to the Pre-Columbian era.One of the permanent exhibitions offers a journey through the customs, people and traditions of Quito, through its displayed history from the sixteenth century to the nineteenth century. Another is the display of the history of the hospital and a collection of items from a former doctor at the hospital. There is another permanent exhibit which is called "A new social order breaks through: Quito nineteenth century".The museum is open Tuesday to Sunday, from 09:30 until 17:30. Admission is free for people with disabilities, certain institutions and municipal employees. Admission for the general public requires minimal fees.

The Ecuador National Museum of Medicine is located in Quito, Ecuador.

Casa del Alabado is a Precolumbian Art Museum in Quito, Ecuador. The museum is located in a colonial house built in the 17th century during the Spanish Colony. It houses a collection of over 5,000 archaeological pieces, 500 of which are on permanent display. Casa del Alabado is unique in the sense that its display is organized thematically, not chronologically. The aim of the museum is to treat objects as works of art rather than archaeological remnants. The display is distributed along 8 rooms with 8 different themes, which serve as representations of cultural aspects of ancient Ecuadorian cultures: their cosmology, their relationship with their ancestors, their religious ideas and rituals, and their relationship with their environment. Casa del Alabado has: Eight exhibit rooms, one room for temporary exhibits, two rooms for workshops, a museum shop and two courtyards.

The Plaza de San Francisco (“Saint Francis Square”) is a major public square in the Historic Center of Quito, Ecuador, upon which faces La Iglesia y Monasterio de San Francisco (the Church and Convent of St. Francis) from which it takes its name.

Alberto Mena Caamaño Museum (Spanish: Museo Alberto Mena Caamaño) is a museum in Quito, Ecuador. A cultural institution of Quito, the capital of Ecuador, it is located in the historic center of the city, next to the Palacio de Carondelet. The Rough Guide to Ecuador considers it to be the "old town's most rewarding museum".It was created by ordinance on May 28, 1957, following a donation from the aristocratic philanthropist Alberto Mena Caamaño. The donation included more than 600 objects including paintings, sculptures, archaeological pieces, weapons and miscellaneous items. After a restoration of the former Royal Barracks building, the museum opened to the public on November 3, 1959. In 1970 a permanent exhibition hall was added on a theme of the slaughter which occurred on August 2, 1810, when 200 citizens were killed in the barracks and the surrounding streets of Quito by royalist troops. It is depicted by wax figures of the artist Francisco Barbieri. In 1987 the museum had to close its doors due to minor damage to the building structure, as a result of the earthquakes that rocked Quito that year. Finally, on November 27, 2002, it reopened following extensive restoration.

San Francisco is a Quito Metro station. It was officially opened on 21 December 2022 as part of the inaugural section of the system between Quitumbe and El Labrador. The revenue service started on 2 May 2023 and discontinued on 11 May 2003. The station is located between La Alameda and La Magdalena.This is an underground station. It has five lifts, ten escalators, and the projected traffic is 69,000 passengers per day.The station is located in the historic center of Quito, in the eastern corner of Plaza San Francisco, at the intersection of Calle Sebastián de Benalcázar and Calle Sucre. One of the entrances has been made in a historic building.On 23 January 2023, the first train with 600 passengers to whom invitations were extended, arrived to the station.

The Church and Convent of San Ignacio de Loyola de la Compañía de Jesús de Quito, also known in the Ecuadorian people simply as La Compañía, is a Catholic clerical complex located on the corner formed by calles García Moreno and Sucre, in the Historic Center of the city of Quito, capital of Ecuador. The façade of its main temple is entirely carved in volcanic stone. Over time, this church has also been called: "Temple of Solomon of South America". Father Bernardo Recio, a traveling Jesuit, called it "Golden Ember". The complex includes the Residencia San Ignacio, "Mother House" of the Jesuits in Ecuador. During colonial times, this "Jesuit block" housed the Seminario San Luis, the Colegio Máximo, the University of San Gregorio Magno and the Mainas Missions Office. Since 1862, the Colegio San Gabriel functioned on the block. The church, and its rich internal ornamentation, completely covered with gold sheets, is one of the main tourist attractions in the city and an invaluable heritage, both artistic and economic, for the country. It was visited by Pope John Paul II, who presided over a mass in the church on January 30, 1985, within the framework of his three-day visit to Ecuador. It was also visited by Pope Francis on July 7, 2015, who prayed there before the image of Our Lady of Sorrows.

The Basilica and Convent of San Francisco (Spanish: Iglesia y Convento de San Francisco), commonly known as el San Francisco, is a Catholic basilica that stands in the middle of the historic center of Quito, in front of the square of the same name. It is the oldest and most significant religious site in Ecuador. The structure is the largest architectural complex within the historic centers of all of South America, and for this reason it was known as "El Escorial of the New World". San Francisco is considered a jewel of continental architecture for its mixture of different styles combined throughout more than 150 years of construction. San Francisco is part of the UNESCO World Heritage Site "City of Quito". On its three and a half hectares of surface, thirteen cloisters have been built (six of them of great magnitude), three temples, a large Atrium, adding approximately 40,000 square meters of construction. Multiple activities are currently carried out there: conventual and religious, public care in the areas of health, communication, education and others of a popular nature that keep the building active. Inside the church there are more than 3,500 works of colonial art, of multiple artistic manifestations and varied techniques, especially those corresponding to the Colonial Quito School of Art, which was born precisely in this place. It also has a Franciscan library, described in the 17th century as the best in the Viceroyalty of Peru. The complex is preceded by the Plaza de San Francisco that for years supplied the city with water from its central fountain, and which has functioned as a popular market, as a space for military and political concentrations, and as a meeting place and social recreation. The concave-convex staircase that connects the square with the Atrium, which highlights the Mannerist-Baroque facade of the main building, is considered of great architectural importance in the Colonial Americas.

Sucre House (Spanish: Museo Casa de Sucre) is a museum in the historic center of Quito, Ecuador. It was established in 1977 by the Ministry of Defence. It is dedicated to the memory of its most famous occupants: the Venezuelan independence hero, Marshal Antonio José de Sucre, and his wife, Mariana Carcelén. The museum contains the personal belongings of the couple, including the original furniture that was occupied in the different rooms of the mansion, everyday items, and even maps and documents from the time of independence. The ground floor contains many of the weapons and military equipment owned by Sucre, while the second floor contains furniture and rooms as they would have appeared in his time.

The Quito Metropolitan Cathedral (Spanish: Catedral Metropolitana de Quito), is a Catholic cathedral in Quito, Ecuador. Located on the southwestern side of the Plaza de la Independencia (La Plaza Grande), it (and its predecessor building) served as a seat of the Diocese of Quito from 1545 until 1848 when it was elevated to Archdiocese. In 1995, it was elevated to the Cathedral of Ecuador, making it the seniormost Catholic church in the country.

Centro Cultural Metropolitano (English: Metropolitan Cultural Center) is a cultural institution based in Quito, Ecuador. It was established in 1997 in a building which dates to 1622. This building belongs to the colonial epoch, but its facade was rebuilt in the 20th century. The First Central University was in this building. It also was a jail where Spanish authorities executed insurgents during the Ecuadorian War of Independence.

La Iglesia de El Sagrario (Spanish, 'Church of the Sanctuary' or 'Church of the Shrine') is a Renaissance Catholic church in the city of Quito, capital of Ecuador. It is located in the Historic Center of the city, on calle García Moreno, formerly known as calle de las Siete Cruces, a few meters from the corner with calle Eugenio Espejo. It is part of the Metropolitan Cathedral complex, although it seems more like an independent church than an adjoining chapel, both because of its size and because of its importance in Quito's art.