Dr. Samuel Mitchel Smith and Sons Memorial Fountain

The Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (commonly shortened to just The James) is part of The Ohio State University Wexner Medical Center and is one of the National Cancer Institute's Comprehensive Cancer Centers. It is named after Arthur G. James, the founder, who desired a cancer hospital in Columbus, Ohio, United States. The hospital treats cancer, and conducts research in the Solove Research Institute. The James receives donations through the Pelotonia biking event. In 2018, the James Cancer Hospital was designated a magnet hospital by the American Nurses Credentialing Center. With its expansion in 2014, it is now the third largest cancer hospital in the United States. Despite sizable fundraising efforts and recognition in Central Ohio, U.S. News & World Report ranked the hospital as the 30th best cancer hospital in the United States in 2020.

The Ohio State University Wexner Medical Center is a multidisciplinary academic medical center located in Columbus, Ohio, United States, on the main campus of The Ohio State University. For 29 consecutive years, U.S. News & World Report has recognized Ohio State Wexner Medical Center specialties in its "Best Hospitals" rankings. In 2021, it recognized 10 Ohio State Wexner Medical Center specialties: Ear, Nose and Throat #8; Diabetes and Endocrinology #19; Cancer #27; Neurology and Neurosurgery #28; Pulmonology and Lung Surgery #29; Urology #31; Rehabilitation #31; Cardiology and Heart Surgery #38; Gynecology #46; and Gastroenterology and GI Surgery #50. USNWR also named the Ohio State Wexner Medical Center the best hospital in central Ohio and the second best hospital in the state.In 2022, only one program was rated in the top 20 (Ear Nose and Throat #19), and two previously ranked programs were unranked (Diabetes and Endocrinology; Urology).

The Ohio State Richard M. Ross Heart Hospital is located at Ohio State University in Columbus, Ohio. The hospital specializes in cardiology, and is ranked number 46 in the United States for its heart program by U.S. News & World Report for 2020. Care is provided for patients with cardiovascular disease or peripheral vascular disease. The hospital was the first in the country to perform robotic surgery.

Prior Hall, originally known as the Health Sciences Library, is the home of the medical library at Ohio State University. The library was named the John A. Prior Health Sciences Library in 1988 and later renamed to Health Sciences Library in Prior Hall.

The Ohio State University College of Medicine (formerly known as The Ohio State University College of Medicine and Public Health) is the medical school at The Ohio State University and is located in Columbus, Ohio. The college is nationally recognized as a top institution in both education and research, as reflected by rankings in U.S. News & World Report,No. 28 (tie) in Best Medical Schools: Research. In 2023, its two primary teaching hospitals (The Ohio State University Wexner Medical Center and Nationwide Children's Hospital) were ranked as one of the best hospitals in the U.S. in 9 and 10 different specialties, respectively; and Nationwide Children's Hospital was named to U.S. News & World Report's select honor roll of U.S. Best Children's hospitals.

The Health Sciences Center for Global Health (HSCGH) at The Ohio State University (OSU) is a collaborative program among the OSU Colleges of Dentistry, Medicine, Nursing, Optometry, Pharmacy, Public Health, School of Health and Rehabilitation Sciences and Veterinary Medicine. The HSCGH is led jointly by the Colleges of Medicine (COM) and Public Health (CPH). The HSCGH was created to increase student interest in global careers, prepare students for those careers and to promote, develop and coordinate interdisciplinary global health education and research throughout the health sciences colleges and the larger community. The Board of Trustees approved the creation of the HSCGH in July 2007.The National Institutes of Health (NIH) Fogarty Framework Grant was awarded to OSU in September 2008. The NIH John E. Fogarty International Center grant supports the creation of new, multidisciplinary educational programs as well as an administrative infrastructure to support activities.

The Ohio State University College of Dentistry is one of the graduate and professional schools of The Ohio State University. The college is the fourth largest public dental school in the U.S. and consists of nine academic divisions representing all major dental specialties. In addition to the Doctor of Dental Surgery (D.D.S.) and Bachelor of Science in Dental Hygiene degrees, the Ohio State College of Dentistry offers specialty training programs, advanced training programs, MS programs, and a Ph.D. program in Oral Biology. Outreach and Engagement activities include over 60 active programs and more than 42 extramural sites, which continue to expand.

The Mathematical Biosciences Institute (MBI) was an institution of higher learning affiliated with the Ohio State University in Columbus, Ohio. MBI received major funding from the National Science Foundation.

The Drake Performance and Event Center was located at Ohio State University. Formerly known as the Drake Union, it was originally constructed as a student activity center before becoming home to the Department of Theater. The center was located on the west campus of Ohio State between Morrill Tower and Lincoln Tower off the east banks of the Olentangy River.

Mirror Lake is a pond on the campus of the Ohio State University in Columbus, Ohio. Visitors, students, faculty, and staff visit the fountains that run in spring, summer, and autumn.

Ohio Stadium is an American football stadium in Columbus, Ohio, on the campus of Ohio State University. It primarily serves as the home venue of the Ohio State Buckeyes football team and is also the site for the university's Spring Commencement ceremonies each May. Common nicknames for the stadium include "The Horseshoe", "The Shoe", and "The House That Harley Built". From 1996 to 1998, Ohio Stadium was the home venue for the Columbus Crew of Major League Soccer prior to the opening of Columbus Crew Stadium in 1999. The stadium also was the home venue for the OSU track and field teams from 1923 to 2001. In addition to athletics, Ohio Stadium is also a concert venue, with U2, Taylor Swift, The Rolling Stones, Genesis, Pink Floyd, and Metallica among the many acts to have played at the venue. The stadium opened in 1922 as a replacement for Ohio Field and had a seating capacity of 66,210. In 1923, a cinder running track was added that was later upgraded to an all-weather track. Seating capacity gradually increased over the years and reached a total of 91,470 possible spectators in 1991. Beginning in 2000, the stadium was renovated and expanded in several phases, removing the track and adding additional seating, which raised the capacity to 101,568 by 2001 and to 102,329 in 2007. In 2014, additional seating was added in the end zone, raising the official capacity to 104,944. Another renovation to add more luxury suites began in 2017 and will eventually lead to a decrease of 2,600 seats. It is the largest stadium by capacity in the state of Ohio, and the third largest on-campus football stadium in the United States. Ohio Stadium was added to the National Register of Historic Places in 1974.

The William Oxley Thompson Memorial Library (commonly referred to as the Thompson Library) is the main library at Ohio State University's Columbus campus. It is the university's largest library and houses its main stacks, special collections, rare books and manuscripts, and many departmental subject libraries. The library was originally built in 1912, and was renovated in 1951, 1977, and 2009. It is named in honor of the university's fifth president, William Oxley Thompson.