23rd Street station (IRT Broadway–Seventh Avenue Line)

Gotham Comedy Club is a venue for stand-up comedy in New York City. The comedy club is located on 208 West 23rd Street between Seventh and Eighth Avenues in Chelsea. Several movies and television shows have been filmed at the club. Numerous mainstream comedians have performed at the venue, including Dave Chappelle, Jerry Seinfeld, Lewis Black, Chris Rock, Dane Cook, Artie Lange, Chris Rush, Colin Quinn, Greg Giraldo, Tom Papa, Adam Ferrara, Jay Mohr, Dean Edwards, Pablo Francisco, Jim Gaffigan, Gabriel Iglesias, Doug Stanhope, Rosie O'Donnell, and Colin Kane.

The Hotel Chelsea (also the Chelsea Hotel or the Chelsea) is a hotel in Manhattan, New York City, built between 1883 and 1885. The 250-unit hotel is located at 222 West 23rd Street, between Seventh and Eighth Avenues, in the neighborhood of Chelsea. It has been the home of numerous writers, musicians, artists and actors. Though the Chelsea no longer accepts new long-term residents, the building is still home to many who lived there before the change in policy. Arthur C. Clarke wrote 2001: A Space Odyssey while staying at the Chelsea, and poets Allen Ginsberg and Gregory Corso chose it as a place for philosophical and artistic exchange. It is also known as the place where the writer Dylan Thomas was staying in room 205 when he became ill and died several days later, in a local hospital, of pneumonia on November 9, 1953, and where Nancy Spungen, girlfriend of Sid Vicious of the Sex Pistols, was found stabbed to death on October 12, 1978. Arthur Miller wrote a short piece, "The Chelsea Affect", describing life at the Chelsea Hotel in the early 1960s.The building has been a designated New York City landmark since 1966, and on the National Register of Historic Places since 1977.

El Quijote is a Spanish restaurant in the Hotel Chelsea in the New York City borough of Manhattan. The eatery has been in the same location (226 West 23rd Street) for some 88 years and, after being sold by the original owning family (under the final aegis of Manny Ramirez) to Chelsea Hotels, it was closed for renovations. The new proprietors have kept the authentic Spanish feel of the place which was reopened in 2022.

High School of Fashion Industries (HSFI) is a secondary school located in Manhattan, New York City, New York. HSFI serves grades 9 through 12 and is a part of the New York City Department of Education. HSFI has magnet programs related to fashion design, fashion art, marketing and visual merchandising, graphics and illustration and photography.

Proctor's Theatre, also known as Proctor's Twenty-Third Street Theatre, RKO Proctor's Twenty-Third Street Theatre and Keith & Proctor's Twenty-Third Street Theatre, was a theatre located in Chelsea, Manhattan at 141 West 23rd St. in-between Sixth Avenue and Seventh Avenue. It was built in 1889 by the theatrical impresario F. F. Proctor on the former site of Salmi Morse's Temple Theatre which was demolished in 1888. The theatre was designed by architect H. Edward Fickens and had a seating capacity of 1,717 people. The theater was used for both legitimate theatre and vaudeville entertainments before being purchased by RKO and becoming a movie theatre. A fire in 1937 forced the theatre to close permanently.

The Irish Repertory Theatre is an Off Broadway theatre founded in 1988.

Red Door was a 2,000 SF event and music space located in the heart of Chelsea, New York City that remained private to the public for 37 years. Its name changed over the years, but always based on the colors of the front door (previous incarnations were Green Door and Purple Door). The venue attracted a wide array of celebrities and personalities in the music and entertainment world.

The Michael Howard Studios is an acting studio for the performing arts located in at 152 West 25th Street in Chelsea, Manhattan, New York City; the studio was founded in 1953 by actor/director Michael Howard.

Barracuda Lounge, or simply Barracuda, is a gay bar in the Chelsea neighborhood of Manhattan in New York City. Opened in 1995, the bar is known for its nightly drag shows. It is a sister establishment to Industry, a nightclub, and Elmo, a restaurant. Barracuda is home to "Star Search", the longest-running bar show in New York City, which began in the early 1990s and may have served as an inspiration for RuPaul's Drag Race. In the 1990s and 2000s, Barracuda was a popular celebrity hangout, and it was frequently the site of promotional events for new music and Broadway plays. While closed for much of 2020 and 2021 due to the COVID-19 pandemic, the venue underwent a major renovation. It reopened in June 2021. Critics generally praise Barracuda for its intimate, relaxed and entertainment-focused atmosphere, which was unusual at the time of its creation, and some credit this with revolutionizing the concept of gay bars.

BurritoVille is a New York City-based quick-service food chain serving Tex-Mex cuisine, established in 1992. Until 2008, there were 16 locations in Manhattan, one in Westbury, New York on Long Island, and one in Hoboken, NJ. The menu items consist mostly of various types of burritos and tacos, as well as salads and nachos. Many of the items are vegetarian. The chain's slogan is, "We're Mexcellent!" Interior decor consists of antique maps of Mexico and classic sensational horror and romance Mexican cinema posters. In September 2008, Burritoville closed all its Manhattan locations as a result of filing for reorganization under the bankruptcy laws. However, the Westbury location remained open for business. In November 2008, one of the former owners of Blimpie purchased BurritoVille and directed a complete makeover of the chain. The Financial District location (36 Water Street), which re-opened in July 2009, was the first of several planned locations in New York City and throughout the country. The 23rd Street location reopened in the fall of 2009. In 2011, Burritoville's website listed only its 23rd Street restaurant in Manhattan as an active location. As of late 2014, the website listed only a single restaurant located in Jersey City, New Jersey.

The Parish of St. Vincent de Paul was a national parish of the Roman Catholic Archdiocese of New York. Founded in 1841, it was dedicated to serve the needs of the French-speaking population of the city. The parish church was located at 123 West 23rd Street, New York, New York. The parish was closed in January 2013.

Poster House is the first museum in the United States dedicated exclusively to posters. The museum is located in Chelsea, New York City, on 23rd Street between and Sixth Avenue and Seventh Avenue. The museum opened to the public on June 20, 2019.