Main and Third Street Cluster

Fort Washington was a fortified stockade with blockhouses built by order of Gen. Josiah Harmar starting in summer 1789 in what is now downtown Cincinnati, Ohio near the Ohio River. The physical location of the fort was facing the mouth of the Licking River, above present day Fort Washington Way. The fort was named in honor of President George Washington. The Fort was the major staging place and conduit for settlers, troops and supplies during the settlement of the Northwest Territory. In 1803, the fort was moved to Newport, KY across the river and became the Newport Barracks. In 1806, the site of the abandoned fort was divided into lots and sold.

The Duke Energy Building (formerly the Cincinnati Gas & Electric Company Building) is a historic, 18-story, 269-foot-tall (82 m) structure in Cincinnati, Ohio. It was designed by Cincinnati architectural firm Garber & Woodward and John Russell Pope.

The Great American Tower at Queen City Square, is a 41-story, 665-foot-tall (203 m) skyscraper in Cincinnati, Ohio which opened in January 2011. The tower was built by Western & Southern Financial Group at a cost of $322 million including $65 million of taxpayer-funded subsidies. Construction on the tower had begun in July 2008. Half the building is occupied by the headquarters of the Great American Insurance Company. It is currently the third tallest building in the state of Ohio, and the tallest outside of Cleveland.

Christ Church Cathedral, Cincinnati is the cathedral church of the Episcopal Diocese of Southern Ohio, United States.

The PNC Center is a 108-meter (354 feet) tall office building located in Cincinnati, Ohio. It is located primarily in the Central Business District and borders Main Street and East Fifth Street. The building's 27 floors are used for office and commercial use. On the southeast corner of Fifth and Main streets is a public plaza. Built in 1979, this skyscraper was the tallest completed in Cincinnati during the 1970s decade. It initially served as headquarters of Central Trust Bank, which PNC acquired in 1988. With the acquisition, PNC also became the lead tenant of the historic PNC Tower, Central Trust's headquarters before the 1979 building was constructed. The building's exterior is typical of 1970s architecture. It features a lightly colored exterior wall with tinted rectangular windows. Unusual for architecture of the time, there are a number of setbacks in the building, both horizontally and vertically. The building has no crown or topped area which is also typical of 1970s architecture. The roof is flat. The building was designed by Skidmore, Owings & Merril.

The Federal Reserve Bank of Cleveland Cincinnati Branch Office is one of two Federal Reserve Bank of Cleveland branch offices (the other is in Pittsburgh). The Cincinnati Office of the Federal Reserve Bank of Cleveland provides currency distribution services for financial institutions in multiple Reserve Districts.James M. Anderson is the current chairman.

The Fourth & Walnut Center (previously known by the names Clopay Building and the First National Bank Building) is a building in Cincinnati, Ohio. It was the tallest in the state from 1904 - 1913. The building was designed by D.H. Burnham and Company and completed in 1904. The architect Daniel Burnham of Chicago designed the Clopay Building (a combination of the words clothing and paper) in the Chicago school. The building was listed on the National Register of Historic Places in 2017.

The Cincinnati Reds Hall of Fame and Museum is an entity established by Major League Baseball's Cincinnati Reds franchise that pays homage to the team's past through displays, photographs and multimedia. It was instituted in 1958 to recognize the career of former Cincinnati Reds players, managers and front-office executives. It is adjacent to Great American Ball Park on the banks of the Ohio River. Currently, the Hall of Fame section is home to 81 inductees. These inductees include players, managers & executives who were involved in Cincinnati's baseball legacy, which dates back to 1869, the year the original Cincinnati Red Stockings took the field. Inductions take place every other year.

The Taft Theatre is a 2,500-seat theater, located in Cincinnati, Ohio. The theatre was built in 1928, as evidenced by its Art Deco interior. All seats are unobstructed, giving every seat a clear view of the stage. It is part of the Masonic Temple Building at Fifth and Sycamore streets. It is home to The Children Theatre of Cincinnati. As of 2010, it is operated by Music & Event Management Inc., a subsidiary of Cincinnati Symphony Orchestra. Music & Event Management Inc. also operates Riverbend Music Center and PNC Pavilion. The theatre underwent $3 million worth of upgrades and renovations for air conditioning, seating, restroom improvements and other amenities.It is used for Broadway shows, concerts, comedy and other special events. The theatre played host to the politically motivated Vote for Change Tour on October 2, 2004, featuring performances by Keb' Mo', Bonnie Raitt and Jackson Browne.

Reds Legends of Crosley Field is a group of bronze sculptures by artist Tom Tsuchiya, located at the main entrance of Great American Ball Park in Cincinnati, Ohio. The sculptures represent four Crosley Field era Cincinnati Reds players: Ted Kluszewski, Ernie Lombardi, Joe Nuxhall and Frank Robinson. These players were selected by a fan vote conducted by the Cincinnati Reds.Kluszewski's statue was unveiled on Opening Day, March 31, 2003, to coincide with the official opening of Great American Ball Park. The statues of Nuxhall and Robinson were dedicated in the summer of that year. Subsequently, Lombardi's statue was unveiled on June 28, 2004.

Great American Ball Park is a baseball stadium in Cincinnati, Ohio. It is the home field of Major League Baseball's Cincinnati Reds. It opened in 2003, replacing Cinergy Field (formerly Riverfront Stadium), their home field from 1970 to 2002.Great American Insurance bought the naming rights to the stadium for $75 million over 30 years.

The Dixie Terminal is a set of buildings in Cincinnati, Ohio, that were completed in 1921 and served as a streetcar terminal, stock exchange, and office building in the city's downtown business district. They were designed by Cincinnati architect Frederick W. Garber's Garber & Woodward firm. The main building includes an Adamesque barrel-vaulted concourse and Rookwood Architectural Faience entry arch. The Rookwood tiles were manufactured by the local Rookwood Pottery Company. At Fourth and Walnut Streets, the terminal was constructed of reinforced concrete and finished in gray brick, Bedford limestone, and granite. It includes two structures: the four-story south building extending to Third Street, where streetcars entered and left, and the "handsome" 10-story north building, housing railroad ticket agencies, the Cincinnati Stock Exchange, administrative offices of the Cincinnati Street Railway Company, commercial offices, and shops.A long and elaborate arcade runs through from main entrance through the building, lined by shops. The building included marble floors, Bottincino marble wainscot, metal trimmings, and "costly brightly decorated ceilings, with fanciful medallions showing little children riding on the backs of various animals".The terminal was used for bus service after streetcar service ceased in the 1950s. Buses arriving from northern Kentucky crossed the Roebling Suspension Bridge and took ramps from the bridge into the terminal. In 1998 the ramps were removed, and the bus service ceased using the terminal. The Cincinnati Stock Exchange closed its physical trading floor in 1976 after becoming an all-electronic stock trading exchange but remained in the building until relocating to Chicago in 1995 as the National Stock Exchange.A scene in the 1988 film Rain Man was shot at Dixie Terminal.