14th Street station (IRT Second Avenue Line)

The First Avenue station is a station on the BMT Canarsie Line of the New York City Subway. Located at the intersection of First Avenue and East 14th Street at the border of Stuyvesant Park, Stuyvesant Town, and the East Village in Manhattan, it is served by the L train at all times.

Chogye International Zen Center is a Kwan Um School of Zen practice center founded by Seung Sahn in 1975, located in New York City. The center offers a daily practice regimen, as well as retreats and workshops. Wu Kwang is the guiding teacher and resident Zen Master, the abbot is Steven Cohen.Prebish, Charles S (1999). Luminous Passage: The Practice and Study of Buddhism in America. University of California Press. pp. 34. ISBN 0-520-21697-0.Morreale, Don (1998). The Complete Guide to Buddhist America. Shambhala Publications. pp. 171.

The City Congregation for Humanistic Judaism, founded in 1991, is the only Humanistic Jewish congregation in Manhattan, and the first Humanistic congregation in New York City to be led by a Humanistic rabbi. The aim of The City Congregation is to provide a welcoming, diverse community for cultural and secular Jews where they can celebrate and preserve their Jewish identity. As adherents of Humanistic Judaism, founded in 1963 by Rabbi Sherwin Wine, TCC members rely on reason, inner strength, and the support of community to face life's challenges and collectively improve the world. TCC members come from throughout the New York metropolitan area and do not claim one specific neighborhood. While they reside predominantly in Manhattan and Brooklyn, they also live in Queens and the Bronx, as well as Westchester, Long Island and New Jersey. The congregation meets for Shabbats at a convenient Midtown location. For adult and child learning, they meet on the Upper West Side, and for High Holidays and Passover they meet in Midtown West. The City Congregation is an affiliated community of the Society for Humanistic Judaism, which was organized in 1969 and comprises more than thirty secular Jewish communities in the United States and Canada.

The Church of the Immaculate Conception is a parish church in the Roman Catholic Archdiocese of New York, located at 414 East 14th Street, near First Avenue, Manhattan, New York City, and previously at 505 East 14th Street.

The Church of the Immaculate Conception and Clergy House at 406–412 East 14th Street between First Avenue and Avenue A in the East Village neighborhood of Manhattan, New York City were built in 1894–1896 by Grace Church, one of the most prominent Episcopal churches in the city at the time. The buildings were a free chapel – meaning there was no pew rent – called Grace Chapel and a connected Grace Hospital, which could serve 16 senior citizens and 10 children, and was physically connected to the chapel by a bridge, so that patients could be wheeled to services.They were designed by Barney and Chapman in French Gothic style. The firm was working at the same time on the Church of the Holy Trinity in Yorkville, which was also designed in the same style. Grace Chapel has stained-glass windows by Clayton & Bell and Henry Holiday. In 1943 both buildings were sold to the Roman Catholic Archdiocese of New York, and were converted for the use of the Immaculate Conception Church, founded in 1855, as a sanctuary and Clergy House.The buildings were designated a New York City landmark in 1966, and were added to the National Register of Historic Places in 1980.

The High School for Health Professions and Human Services is a public high school in Manhattan, New York City. It is specialized for students preparing for careers in the healthcare and human resources fields.The curriculum emphasizes the academic preparation necessary for these fields. Students take four years of both mathematics and science, and there are elective research programs and college level courses in both the sciences and the humanities. The High School for Health Professions and Human Services offers a range of science courses as part of a traditional high school curriculum. Top students may conduct research with mentors at nearby hospitals and a few may even compete in the Intel Science Talent Search. The school also offers courses in nutrition, forensics, and a combined art and anatomy class.

Open Road Park is a small park in East Village, Manhattan, New York City, located east of First Avenue between 11th and 12th Streets. It is among the larger green spaces created in the East Village as a result of community organizing. The site of this park was taken over in 1993 by Open Road, a neighborhood nonprofit that developed the lot into a community garden and playground. Prior to its use as a park, the site was used for many purposes that reflect on the history of the surrounding neighborhood.

Mount Sinai Beth Israel is a 799-bed teaching hospital in Manhattan. It is part of the Mount Sinai Health System, a nonprofit health system formed in September 2013 by the merger of Continuum Health Partners and Mount Sinai Medical Center, and an academic affiliate of the Icahn School of Medicine at Mount Sinai.

East Side Community High School is a public school at 420 East 12th Street in the East Village neighborhood of Manhattan in New York City. Founded in 1991, it is for students from the 6th to 12th grade. Its principal is Mark Federman. Girls Prep, a charter school, is housed inside the same building. The building also housed Ross Global Academy, another charter school, until 2011.

New York Eye and Ear Infirmary of Mount Sinai (NYEE) is located at East 14th Street and Second Avenue in lower Manhattan, New York City. Founded on August 14, 1820, NYEE is America's first specialty hospital and one of the most prominent in the fields of ophthalmology and otolaryngology in the world, providing primary inpatient and outpatient care in those specialties. Previously affiliated with New York Medical College, as of 2013 it is affiliated with the Icahn School of Medicine at Mount Sinai as a part of the membership in the Mount Sinai Health System.

Harry & Ida's Meat and Supply Co. was a smokehouse and delicatessen located in Alphabet City, Manhattan, New York City that operated from 2015 to 2019.

Foxface Natural is a restaurant in New York City.