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National Human Genome Research Institute

1989 establishments in MarylandGenetics or genomics research institutionsMedical research institutes in MarylandNational Institutes of Health
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The National Human Genome Research Institute (NHGRI) is an institute of the National Institutes of Health, located in Bethesda, Maryland. NHGRI began as the Office of Human Genome Research in The Office of the Director in 1988. This Office transitioned to the National Center for Human Genome Research (NCHGR), in 1989 to carry out the role of the NIH in the International Human Genome Project (HGP). The HGP was developed in collaboration with the United States Department of Energy (DOE) and began in 1990 to sequence the human genome. In 1993, NCHGR expanded its role on the NIH campus by establishing the Division of Intramural Research (DIR) to apply genome technologies to the study of specific diseases. In 1996, the Center for Inherited Disease Research (CIDR) was also established (co-funded by eight NIH institutes and centers) to study the genetic components of complex disorders. In 1997 the United States Department of Health and Human Services (DHHS) renamed NCHGR the National Human Genome Research Institute (NHGRI), officially elevating it to the status of research institute – one of 27 institutes and centers that make up the NIH. The institute announced the successful sequencing of the human genome in April 2003, but there were still gaps remaining until the release of T2T-CHM13 by the Telomere-to-Telomere Consortium.

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National Human Genome Research Institute
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National Institutes of Health

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20814 Bethesda
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National Institutes of Health Clinical Center
National Institutes of Health Clinical Center

The NIH Clinical Center is a hospital solely dedicated to clinical research at the National Institutes of Health campus in Bethesda, Maryland. The Clinical Center, known as Building 10, consists of the original part of the hospital, the Warren Grant Magnuson Clinical Center, and the newest addition, the Mark O. Hatfield Clinical Research Center. The two parts are connected to form one large building.Since the hospital's opening in 1953, NIH scientists have worked with volunteer patients to create medical innovations. Clinical Center successes include pioneering the cure of cancerous solid tumors with chemotherapy; the use of nitroglycerin to treat heart attacks; identifying a genetic component in schizophrenia; conducting the first successful replacement of a mitral valve to treat heart disease; and the creation of blood tests to identify both Acquired Immune Deficiency Syndrome (AIDS) and hepatitis.In October 2014, Clinical Center staff successfully treated one of the first few Ebola virus cases in the United States. The Clinical Center has been a leader in the “bench-to-bedside” concept. Its specialized hospital design places patient care units in close proximity to research laboratories. This model supports interaction and collaboration among clinical researchers. The Clinical Center also provides training opportunities for students, new and mid-career professionals. A Summer Internship Program offers internships to students who are currently enrolled in high school, college, graduate programs and health professional schools such as nursing or medicine. The Medical Research Scholars Program is a year-long research enrichment program designed for research-oriented medical, dental and veterinary students. The Clinical Research Management Sabbatical is a self-directed educational experience designed for clinical research investigators and managers of clinical research programs. The Clinical Center also provides a course called the Introduction to the Principles and Practice of Clinical Research to train physicians, scientists, medical students, nurses and other health professionals how to effectively conduct clinical research.

National Institutes of Health
National Institutes of Health

The National Institutes of Health, commonly referred to as NIH (with each letter pronounced individually), is the primary agency of the United States government responsible for biomedical and public health research. It was founded in the late 1880s and is now part of the United States Department of Health and Human Services. Many NIH facilities are located in Bethesda, Maryland, and other nearby suburbs of the Washington metropolitan area, with other primary facilities in the Research Triangle Park in North Carolina and smaller satellite facilities located around the United States. The NIH conducts its own scientific research through the NIH Intramural Research Program (IRP) and provides major biomedical research funding to non-NIH research facilities through its Extramural Research Program. As of 2013, the IRP had 1,200 principal investigators and more than 4,000 postdoctoral fellows in basic, translational, and clinical research, being the largest biomedical research institution in the world, while, as of 2003, the extramural arm provided 28% of biomedical research funding spent annually in the U.S., or about US$26.4 billion.The NIH comprises 27 separate institutes and centers of different biomedical disciplines and is responsible for many scientific accomplishments, including the discovery of fluoride to prevent tooth decay, the use of lithium to manage bipolar disorder, and the creation of vaccines against hepatitis, Haemophilus influenzae (HIB), and human papillomavirus (HPV).In 2019, the NIH was ranked number two in the world, behind Harvard University, for biomedical sciences in the Nature Index, which measured the largest contributors to papers published in a subset of leading journals from 2015 to 2018.

National Institute of General Medical Sciences
National Institute of General Medical Sciences

The National Institute of General Medical Sciences (NIGMS) supports basic research that increases understanding of biological processes and lays the foundation for advances in disease diagnosis, treatment, and prevention. NIGMS-funded scientists investigate how living systems work at a range of levels, from molecules and cells to tissues and organs, in research organisms, humans, and populations. Additionally, to ensure the vitality and continued productivity of the research enterprise, NIGMS provides leadership in training the next generation of scientists, in enhancing the diversity of the scientific workforce, and in developing research capacity throughout the country. NIGMS is one of the National Institutes of Health (NIH), the principal medical research agency of the Federal Government. NIH is a component of the U.S. Department of Health and Human Services. All NIH Institutes and Centers support basic research that is relevant to the diseases, organ systems, stages of life, or populations within their mission areas. In contrast, NIGMS supports fundamental research that does not focus on those specific areas. NIGMS' research mission is aimed at understanding the principles, mechanisms, and processes that underlie living organisms, often using research models. NIGMS also supports the development of fundamental methods and new technologies to achieve its mission. NIGMS-supported research may utilize specific cells or organ systems if they serve as models for understanding general principles. Research with the overall goal to gain knowledge about a specific organ or organ system or the pathophysiology, treatment, or cure of a specific disease or condition will, in most cases, be more appropriate for another Institute or Center. See the NIH listing of Institutes, Centers, and Offices to learn more about their specific missions. NIGMS also supports research in specific clinical areas that affect multiple organ systems: anesthesiology and peri-operative pain; sepsis; clinical pharmacology that is common to multiple drugs and treatments; and trauma, burn injury, and wound healing. NIGMS is organized into the following divisions that support research, research training, and capacity building in a range of scientific fields. Division of Biophysics, Biomedical Technology, and Computational Biosciences Division of Genetics and Molecular, Cellular, and Developmental Biology Division of Pharmacology, Physiology, and Biological Chemistry Division for Research Capacity Building Division of Training, Workforce Development, and DiversityNIGMS was established in 1962. In Fiscal Year 2017, the institute's budget was $2.6 billion. The vast majority of this money funds grants to scientists at universities, medical schools, hospitals, and other research institutions throughout the country. At any given time, NIGMS supports more than 3,000 investigators and 4,000 research grants—around 11 percent of the total number of research grants funded by NIH as a whole. Additionally, NIGMS supports approximately 26 percent of the NRSA trainees who receive assistance from NIH. NIGMS produces a number of free science education materials on topics such as cell biology, genetics, chemistry, pharmacology, structural biology, and computational biology. The institute also produces the magazine Findings, which showcases diverse scientists who do cutting-edge research and lead interesting lives.

Congregation Beth El (Bethesda, Maryland)
Congregation Beth El (Bethesda, Maryland)

Congregation Beth El is a synagogue located in Bethesda, Maryland. Beth El is an egalitarian synagogue providing diverse worship in the Conservative tradition.Congregation Beth El started in 1951 as a synagogue of 16 families and has grown to approximately 1,000 families.Greg Harris is Rabbi, Deborah Megdal is Associate Rabbi, and Bill Rudolph is Rabbi Emeritus. Asa Fradkin is Hazzan and Abe Lubin is Hazzan Emeritus. Rudolph, Harris, and Lubin have each been featured on the PBS television program Religion & Ethics Newsweekly.Congregation Beth El is housed in a modern structure of approximately 60,000 square feet (5,600 m2) on Old Georgetown Road. On the bimah of the main sanctuary are two large tapestries, installed in September 1997. Created by local artist Tamar Fishman and executed by British weaver Pat Johns, the tapestries are inspired by two narratives from the Book of Genesis that envision episodes in the life of the patriarch Jacob. One tapestry, named Beth El, reflects Genesis 28:10–19, and the other, named Israel, reflects Genesis 32:25–32. The tapestry Beth El was dedicated by former congregation President Walter Arnheim.Congregation Beth El has received recognition for its award-winning adult education program, the Saul Bendit Institute. Beth El's adult b'nai mitzvah ceremony received special notice in 2010 when 94-year-old Esther Isralow became the oldest of 19 congregants to complete the 18 months of study led by Rabbi Harris that culminated in the service. And Congregation Beth El has held interfaith seminars, such as a 2010 seminar on leadership with perspectives from the Hebrew Bible, the New Testament, and the Koran.In 2008, Congregation Beth El received a grant from the Pathways Awareness Foundation recognizing its actions to include worshippers of all abilities. In 2009, the United Synagogue of Conservative Judaism gave Beth El an award for the quality of its bulletins.