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Fayette Street Conservation Area is located near downtown Indianapolis, off of the I-65 North and near the IU Indianapolis campus. It overlaps with both downtown Indy as well as some historical districts in Indianapolis, such as Lockefield Gardens. Much of the campus' land was taken from the original neighborhood. It is associated with the White River/Central Canal area of downtown Indy because of its close proximity.. It used to be a majority black settlement in the Canal area, one of the few available. It is also part of the Historic Urban Neighborhoods of Indianapolis (HUNI). It is listed as a "Water Landmark" by the American Water Works Association, and as a Historic District in the Indianapolis Historic Preservation Commission (IHPC). It was established as a historic district in 1995. Fayette Street is down the street from Massachusetts Avenue and Lockefield Gardens. Its bounds are 9th Street, 10th Street, Martin Luther King Jr. Street and North Missouri Street. It was first designed in the 1800s, and reuptake began in 1995, when it was also by the IHPC. Some landmarks in the area are the Madame CJ Walker Theatre, the Kurt Vonnegut museum, and the USS Indianapolis Memorial. A revitalization effort was designed for the neighborhood due to the deterioration. A well-known traffic cam was placed in the area, tracking traffic on the I-65.

The Kahn Tailoring Company building is a historic structure located in downtown Indianapolis, Indiana. It was designed by Indianapolis architects Vonnegut & Bohn and built in 1913. The building is a four-story Neoclassical style structure with reinforced concrete behind a brick veneer. The front entrance features a cornice with decorative features.This building served as the manufacturing headquarters for the Kahn Tailoring Company, started by Henry Kahn in 1903. In addition to the manufacturing building, Kahn operated a retail store at 7 North Meridian Street in Indianapolis. Kahn was known for their high-end, custom suits for men and women. It was also an important manufacturer of military uniforms for the United States during World War I and World War II.In 1954, Kahn Tailoring Company merged with the Globe Tailoring Company of Cincinnati, Ohio, and moved its manufacturing operations to Globe's facilities. The building was sold to a local printing company, who occupied it until at least the late-1990s. The building fell into disrepair before being converted into apartments in 2014.The building was listed on the National Register of Historic Places in 2019.

The Stutz Motor Car Company was an American automobile manufacturer based in Indianapolis, Indiana that produced high-end sports and luxury cars. The company was founded in 1911 as the Ideal Motor Car Company before merging with the Stutz Auto Parts Company in 1913. Due to the pressures of the Great Depression, the Stutz company went defunct in 1938. The Stutz Motor Car Company produced roughly 39,000 automobiles in their Indianapolis factory during their existence. The Stutz brand was revived in 1968 as Stutz Motor Car of America, with a focus on producing Neoclassic automobiles. The company is still in existence, but sales of factory-produced vehicles ceased in 1995.

Untitled (Jazz Musicians) is an outdoor sculpture by American artist John Spaulding. It is located on the border of Indiana University-Purdue University Indianapolis (IUPUI) campus, near downtown Indianapolis, Indiana, at the corner intersection of Indiana Avenue and West Street. The sculpture faces the historic Madam Walker Legacy Center, which is located across the street.

The Kurt Vonnegut Museum and Library is dedicated to championing the literary, artistic, and cultural contributions of the late writer, artist, and Indianapolis native Kurt Vonnegut, Jr. It opened in January 2011 and was located in The Emelie, a structure on the National Register of Historic Places at 340 North Senate Avenue in Indianapolis, Indiana, until January 2019. Funding for a new building at 543 Indiana Avenue was secured, and the library reopened to the public on November 9, 2019. The library serves as a cultural and educational resource facility, museum, art gallery, and reading room. It supports language and visual arts education through programs and outreach activities with other local arts organizations to foster a strong arts network for both the local and national communities. One of the goals of the Kurt Vonnegut Museum and Library is to help bring tourism to Indianapolis. Tourism officials from the city look at the library as an important attraction and reason for people to visit. The library is one of several efforts supported by the city and institutions such as the Lilly Endowment and Ball State University to expand the city's cultural activities, alongside the Indianapolis Museum of Art and The Children's Museum of Indianapolis.Ball State University along with partner contributors granted the library $76,710 to digitize rare archival material and make the content more accessible to the general public via a digital display.On September 26, 2021, AP News reported that the Kurt Vonnegut Museum and Library in Indianapolis has been designated a Literary Landmark by the Literary Landmarks Association.

The Madam C. J. Walker Building, which houses the Madam Walker Legacy Center, was built in 1927 in the city of Indianapolis, in the U.S. state of Indiana, and as Madam C. J. Walker Manufacturing Company, it was designated a National Historic Landmark in 1991. The four-story, multi-purpose Walker Building was named in honor of Madam C. J. Walker, the African American hair care and beauty products entrepreneur who founded the Madam C. J. Walker Manufacturing Company, and designed by the Indianapolis architectural firm of Rubush & Hunter. The building served as the world headquarters for Walker's company, as well as entertainment, business, and commercial hub along Indiana Avenue for the city's African American community from the 1920s to the 1950s. The historic gathering place and venue for community events and arts and cultural programs were saved from demolition in the 1970s. The restored building, which includes African, Egyptian, and Moorish designs, is one of the few remaining African-Art Deco buildings in the United States. The Walker Building was added to the National Register of Historic Places in 1980.

The Indianapolis Cultural Trail, officially the Indianapolis Cultural Trail: A Legacy of Gene & Marilyn Glick, is an 8.1-mile-long (13.0 km) urban shared-use path and linear park located in the vicinity of downtown Indianapolis, Indiana. The trail is often compared to other popular bicycle and pedestrian paths across the U.S. and has inspired similar projects throughout the U.S. and Canada.

The Chris Gonzalez Collection, formerly the Chris Gonzalez Library and Archives, is a special collection housed at the Central Library of the Indianapolis Public Library in Indianapolis, Indiana, United States. The collection contains more than 7,000 materials focused on local and national LGBTQ+ issues and history. Its namesake, Christopher T. Gonzalez, was a local LGBTQ+ activist and founder of Indiana Youth Group. In 2019, Indy Pride partnered with the Indianapolis Public Library to open the collection to the public.

Indiana Avenue is a historic area in downtown and is one of seven designated cultural districts in Indianapolis, Indiana. Indiana Avenue was, during its glory days, an African American cultural center of the area. The Indiana Avenue Historic District within the area was designated a United States national historic district in 1987.

Gibson Company Building is a historic industrial / commercial building located at Indianapolis, Indiana. It was built in 1916–1917, and is a five-story, rectangular reinforced concrete building over a basement. It has brick and terra cotta curtain walls. The building features Chicago style windows with Italian Renaissance style detailing. It was originally built to house an automobile assembler, supplier, and showroom.: 5 It was listed on the National Register of Historic Places in 2009.

Glory is a sculpture created by American artist Garry R. Bibbs in 1999. The sculpture is installed above the entrance to the J. F. Miller Center, at the corner of West Michigan Street in Indianapolis, Indiana. Glory is made from fabricated steel and bronze. Angels and trumpets are the two distinct images visible within the sculpture. The sculpture is very large, with dimensions of 80 ft x 40 ft x 1 ft. Gibbs signed his name to the sculpture and included a copyright sign.

The Black Lives Matter street mural in Indianapolis is a large, colorful mural reading "#BLACKLIVESMATTER", with a raised fist, that 18 artists painted across a downtown roadway in August 2020, as part of the George Floyd protests. The mural is located on Indiana Avenue, the historic hub of the city's Black culture, on the same corner as the Madam C. J. Walker Building. 18 individual local African American artists created the artwork, each artist responsible for one of the images in the message, and organized activists working with local Black Lives Matter groups. In contrast to several of the other Black Lives Matter street murals created around the same time, Indianapolis's is not painted in yellow road markings, but instead consists of many different contributions from artists painting in their own distinct style, which comes together as a single artwork.